Green tea catechin induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2 (TRPM2)

被引：5
|
作者：
Monobe, Manami [1 ]
Ema, Kaori [1 ]
Tokuda, Yoshiko [1 ]
Maeda-Yamamoto, Mari [2 ]
机构：
[1] NARO Inst Vegetable & Tes Sci, Shizuoka 4288501, Japan
[2] NARO Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan
来源：
CYTOTECHNOLOGY | 2014年 / 66卷 / 04期
关键词：
(-)-Epigallocatechin (EGC); (-)-Epigallocatechin gallate (EGCG); Phagocytosis; TRPM2; Hydrogen peroxide; HYDROGEN-PEROXIDE; OXIDATIVE DAMAGE; DENDRITIC CELLS; EGCG; MONOCYTES; DNA;
D O I：
10.1007/s10616-013-9618-7
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The major polyphenols in green tea, (-)-epigallocatechin and (-)-epigallocatechin gallate, have been shown to enhance the phagocytic activity of macrophage-like cells; however, the mechanism involved was not clarified. In this study, we have identified that the catechins induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2.
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页码：561 / 566
页数：6
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