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On-demand Therapy for Hereditary Angioedema
被引:3
|作者:
Bernstein, Jonathan A.
[1
]
机构:
[1] Univ Cincinnati, Allergy Sect, Div Immunol, Dept Internal Med,Coll Med, Cincinnati, OH 45267 USA
关键词:
Hereditary angioedema;
On-demand therapies;
Berinert;
Ecallantide;
Icatibant;
Ruconest;
Guidelines;
RECOMBINANT HUMAN C1-INHIBITOR;
C1 INHIBITOR CONCENTRATE;
ACUTE ATTACKS;
RECEPTOR ANTAGONIST;
CONESTAT ALPHA;
MANAGEMENT;
ECALLANTIDE;
DEFICIENCY;
ICATIBANT;
EFFICACY;
D O I:
10.1016/j.iac.2013.07.004
中图分类号:
R392 [医学免疫学];
学科分类号:
100102 ;
摘要:
Consensus guidelines on hereditary angioedema (HAE) recommend that all patients have access to on-demand treatment of acute attacks. A recent patientcentric guideline recommended that at least 2 on-demand therapies be available because patients often have heterogeneous responses to different medications. Self-administration of therapeutic agents, or administration under supervision by a health care provider in the home setting, is the preferred treatment approach. Future studies are needed to show the benefits of acute on-demand therapies at improving quality of life and reducing morbidity and mortality in patients with HAE.
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页码:487 / +
页数:10
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