On-demand Therapy for Hereditary Angioedema

被引：3

作者：

Bernstein, Jonathan A. ^{[1
]}

机构：

[1] Univ Cincinnati, Allergy Sect, Div Immunol, Dept Internal Med,Coll Med, Cincinnati, OH 45267 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2013年 / 33卷 / 04期

关键词：

Hereditary angioedema; On-demand therapies; Berinert; Ecallantide; Icatibant; Ruconest; Guidelines; RECOMBINANT HUMAN C1-INHIBITOR; C1 INHIBITOR CONCENTRATE; ACUTE ATTACKS; RECEPTOR ANTAGONIST; CONESTAT ALPHA; MANAGEMENT; ECALLANTIDE; DEFICIENCY; ICATIBANT; EFFICACY;

D O I：

10.1016/j.iac.2013.07.004

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Consensus guidelines on hereditary angioedema (HAE) recommend that all patients have access to on-demand treatment of acute attacks. A recent patientcentric guideline recommended that at least 2 on-demand therapies be available because patients often have heterogeneous responses to different medications. Self-administration of therapeutic agents, or administration under supervision by a health care provider in the home setting, is the preferred treatment approach. Future studies are needed to show the benefits of acute on-demand therapies at improving quality of life and reducing morbidity and mortality in patients with HAE.

引用

页码：487 / +

页数：10

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