A novel cDNA encoding for a LIM domain protein located at human chromosome 14q32 as a candidate for leukemic translocation

被引：0

作者：

Tsui, SKW ^{[1
]}

Chan, PPK ^{[1
]}

Cheuk, CW ^{[1
]}

Liew, CC ^{[1
]}

Waye, MMY ^{[1
]}

Fung, KP ^{[1
]}

Lee, CY ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CLIN BIOCHEM,TORONTO,ON M5G 1L5,CANADA

来源：

BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL | 1996年 / 39卷 / 04期

关键词：

Homo sapiens; heart cDNA; chromosome; 14; leukemia;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A full-length cDNA clone encoding a zinc finger protein was isolated and sequenced. This full-length clone consists of 728 bp and has a predicted open reading frame (ORF) encoding 208 amino acids. The ORF of this polypeptide codes for the human cysteine-rich protein 2 (HCRP2) and has an amino acid sequence that is 92.8% identical to its rat homolog (RCRP2). HCRP2 was mapped to chromosome 14q32, which is a hot spot of translocation in tumor development, by fluorescent in situ hybridization (FISH).

引用

页码：747 / 754

页数：8

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