A novel cDNA encoding for a LIM domain protein located at human chromosome 14q32 as a candidate for leukemic translocation

被引：0
|
作者：
Tsui, SKW [1 ]
Chan, PPK [1 ]
Cheuk, CW [1 ]
Liew, CC [1 ]
Waye, MMY [1 ]
Fung, KP [1 ]
Lee, CY [1 ]
机构：
[1] UNIV TORONTO,DEPT CLIN BIOCHEM,TORONTO,ON M5G 1L5,CANADA
来源：
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL | 1996年 / 39卷 / 04期
关键词：
Homo sapiens; heart cDNA; chromosome; 14; leukemia;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A full-length cDNA clone encoding a zinc finger protein was isolated and sequenced. This full-length clone consists of 728 bp and has a predicted open reading frame (ORF) encoding 208 amino acids. The ORF of this polypeptide codes for the human cysteine-rich protein 2 (HCRP2) and has an amino acid sequence that is 92.8% identical to its rat homolog (RCRP2). HCRP2 was mapped to chromosome 14q32, which is a hot spot of translocation in tumor development, by fluorescent in situ hybridization (FISH).
引用
收藏
页码：747 / 754
页数：8
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