INTERINDIVIDUAL VARIABILITY OF ORGANIC CATION TRANSPORTER OCT1 (SLC22A1) AND OCT3 (SLC22A3) EXPRESSION IN HUMAN LIVER

被引:0
|
作者
Nies, Anne T. [1 ]
Schaeffeler, Elke [1 ]
Klein, Kathrin [1 ]
Zanger, Ulrich M. [1 ]
Kerb, Reinhold [1 ]
Koepsell, Hermann [2 ]
Keppler, Dietrich [3 ]
Schwab, Matthias [1 ]
机构
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany
[2] Univ Wurzburg, Inst Anat & Cell Biol, D-97070 Wurzburg, Germany
[3] Deutsch Krebsforschungszentrum, Div Tumor Biochem, D-69120 Heidelberg, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
215
引用
收藏
页码:153 / 154
页数:2
相关论文
共 50 条
  • [31] Organic Cation Transporter 3 (OCT3/SLC22A3) and Multidrug and Toxin Extrusion 1 (MATE1/SLC47A1) Transporter in the Placenta and Fetal Tissues: Expression Profile and Fetus Protective Role at Different Stages of Gestation
    Ahmadimoghaddam, Davoud
    Zemankova, Lenka
    Nachtigal, Petr
    Dolezelova, Eva
    Neumanova, Zuzana
    Cerveny, Lukas
    Ceckova, Martina
    Kacerovsky, Marian
    Micuda, Stanislav
    Staud, Frantisek
    [J]. BIOLOGY OF REPRODUCTION, 2013, 88 (03)
  • [32] Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene
    Jonker, JW
    Wagenaar, E
    Mol, CAAM
    Buitelaar, M
    Koepsell, H
    Smit, JW
    Schinkel, AH
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (16) : 5471 - 5477
  • [33] Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)
    Jonker, JW
    Schinkel, AH
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2004, 308 (01): : 2 - 9
  • [34] Effects of obesity on the hepatic expression of organic cation transporter 1 (SLC22A1)
    Ko, Jeong-Hyeon
    Choi, Wun-Seok
    Jang, Eun-Hee
    Kim, Hyoung-Kwang
    Park, Chang-Shin
    Kang, Ju-Hee
    [J]. MOLECULAR & CELLULAR TOXICOLOGY, 2009, 5 (03) : 66 - 66
  • [35] Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
    Bourdet, DL
    Pritchard, JB
    Thakker, DR
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 315 (03): : 1288 - 1297
  • [36] Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3
    L Chen
    C Hong
    E C Chen
    S W Yee
    L Xu
    E U Almof
    C Wen
    K Fujii
    S J Johns
    D Stryke
    T E Ferrin
    J Simko
    X Chen
    J F Costello
    K M Giacomini
    [J]. The Pharmacogenomics Journal, 2013, 13 : 110 - 120
  • [37] Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3
    Chen, L.
    Hong, C.
    Chen, E. C.
    Yee, S. W.
    Xu, L.
    Almof, E. U.
    Wen, C.
    Fujii, K.
    Johns, S. J.
    Stryke, D.
    Ferrin, T. E.
    Simko, J.
    Chen, X.
    Costello, J. F.
    Giacomini, K. M.
    [J]. PHARMACOGENOMICS JOURNAL, 2013, 13 (02): : 110 - 120
  • [38] Interaction of H2-antagonists with human organic cation transporters hOCT1 (SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
    Bourdet, DL
    Pritchard, JB
    Thakker, DR
    [J]. DRUG METABOLISM REVIEWS, 2004, 36 : 262 - 262
  • [39] Effect of Genetic Polymorphisms of Human SLC22A3 in the 5′-flanking Region on OCT3 Expression and Sebum Levels in Human Skin
    Takechi, Tomoki
    Hirota, Takeshi
    Fujii, Kazushi
    Nakahara, Takeshi
    Sakai, Tatsuya
    Maeda, Natsumi
    Furue, Masutaka
    Ieiri, Ichiro
    [J]. JOURNAL OF DERMATOLOGICAL SCIENCE, 2021, 101 (01) : 4 - 13
  • [40] Analysis of the gene structure of the human (SLC22A3) and murine (Slc22a3) extraneuronal monoamine transporter
    Wieland, A
    Hayer-Zillgen, M
    Bönisch, H
    Brüss, M
    [J]. JOURNAL OF NEURAL TRANSMISSION, 2000, 107 (10) : 1149 - 1157