Doublecortin-like kinase 1 (DCLK1) correlates with Notch pathway signaling, controls metastatic characteristics in head and neck cancer

被引：0
|
作者：
Broner, Esther Channah [1 ]
Subbannayya, Tejaswini [2 ]
Advani, Jayshree [2 ]
Zhavoronkov, Alex [3 ]
Artemov, Artem [3 ]
Ozerov, Ivan [3 ]
Sloma, Ido [4 ]
Gowda, Harsha [2 ]
Sidransky, David [1 ]
Izumchenko, Eugene [1 ]
Chatterjee, Aditi [2 ]
机构：
[1] Johns Hopkins Univ, Baltimore, MD USA
[2] Inst Bioinformat, Bangalore, Karnataka, India
[3] Johns Hopkins Univ, Insilico Med Inc, ETC, Baltimore, MD USA
[4] Champ Oncol, Baltimore, MD USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2018-4512
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4512
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma
    Broner, Esther C.
    Trujillo, Jonathan A.
    Korzinkin, Michael
    Subbannayya, Tejaswini
    Agrawal, Nishant
    Ozerov, Ivan, V
    Zhavoronkov, Alex
    Rooper, Lisa
    Kotlov, Nikita
    Shen, Le
    Pearson, Alexander T.
    Rosenberg, Ari J.
    Savage, Peter A.
    Mishra, Vasudha
    Chatterjee, Aditi
    Sidransky, David
    Izumchenko, Evgeny
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [2] Doublecortin-like kinase 1 (DCLK1) is novel Notch pathway signaling regulator in HNSCC
    Broner, Esther Channah
    Subbannayya, Tejaswini
    Zhavoronkov, Alex
    Korzinkin, Mike
    Artemov, Artem
    Ozerov, Ivan
    Sloma, Ido
    Sidransky, David
    Chatterjee, Aditi
    Izumchenko, Evgeny
    CANCER RESEARCH, 2019, 79 (13)
  • [3] Doublecortin-like Kinase 1 (DCLK1) correlates with the cell proliferation in malignant pleural mesothelioma
    Miura, Akihiro
    Yamamoto, Hiromasa
    Tao, Hiroyuki
    Suzawa, Ken
    Miyauchi, Syunsaku
    Araki, Kota
    Takahashi, Yuta
    Kurihara, Eisuke
    Ogoshi, Yusuke
    Shien, Kazuhiko
    Soh, Junichi
    Okabe, Kazunori
    Tomida, Shuta
    Sakaguchi, Masakiyo
    Toyooka, Shinichi
    CANCER RESEARCH, 2019, 79 (13)
  • [4] Targeting Doublecortin-like Kinase 1 (DCLK1) in Colon Cancer: An <it>In</it>-<it>silico</it> Approach
    Parsai, Janhvi
    Crockett, Cooper
    Kimball, Hunter
    Raval, Nipam
    FASEB JOURNAL, 2020, 34
  • [5] Doublecortin-like kinase 1 (DCLK1) and NOTCH1 pathways lead to poor prognosis in HNSCC
    Broner, Esther Channah
    Rooper, Lisa
    Subbannayya, Tejaswini
    Chatterjee, Aditi
    Sidransky, David
    Izumchenko, Evgeny
    CANCER RESEARCH, 2020, 80 (16)
  • [6] Enhanced Expression of Doublecortin-Like Kinase 1 (DCLK1) in the Background Mucosa of Colon Cancer
    Hirata, Yuki
    Sezaki, Takuhito
    Hagiwara, Teruki
    Edogawa, Shoko
    Okada, Toshihiko
    Inoue, Takuya
    Yano, Hideaki
    Gohda, Yoshimasa
    Suda, Ryuichiro
    Hirose, Yoshinobu
    Kawamura, Yutaka J.
    Higuchi, Kazuhide
    Dohi, Taeko
    Kawamura, Yuki I.
    GASTROENTEROLOGY, 2015, 148 (04) : S572 - S572
  • [7] ROLE OF DOUBLECORTIN-LIKE KINASE 1 (DCLK1) POSITIVE TUFT CELLS IN COLITIS-ASSOCIATED COLORECTAL CANCER
    Shin, Alice E.
    Fazio, Elena N.
    Zhang, Liyue
    Good, Hayley
    Sherman, Philip M.
    Wang, Timothy C.
    Asfaha, Samuel
    GASTROENTEROLOGY, 2018, 154 (06) : S23 - S23
  • [8] Specific human cholangiocarcinoma (CCA) subpopulations of cancer stem cells (CSCs) express DoubleCortin-Like Kinase 1 (DCLK1) and DCLK1 inhibition induces anti-cancer effects
    Nevi, L.
    Di Matteo, S.
    Carpino, G.
    Cardinale, V.
    Zizzari, I.
    Ambrosino, V.
    Costantini, D.
    Safarikia, S.
    Manzi, E.
    Derose, A. M.
    Melandro, F.
    Bragazzi, M. C.
    Grazi, G.
    Berloco, P. B.
    Giuliante, F.
    Gaudio, E.
    Alvaro, D.
    DIGESTIVE AND LIVER DISEASE, 2018, 50 (01) : 5 - 6
  • [9] A putative stem cell marker, doublecortin-like kinase (DCLK1), is involved in the development of hepatocellular carcinoma
    Ali, Naushad
    CANCER RESEARCH, 2013, 73 (08)
  • [10] First-in-class Doublecortin-like kinase 1 (DCLK1) inhibitor for targeting cancer stem cell in hepatocellular carcinoma.
    Yoon, Daseul
    Jung, Seung Hee
    Jang, Ju Young
    Ahn, Ji-Young
    Jo, Seung Jin
    Ko, Donghyun
    Kim, Dong-kyu
    Yu, Su Jong
    CANCER RESEARCH, 2022, 82 (12)
12345