Treatment with human chorionic gonadotropin (hCG) for ovulation induction is associated with an immediate 17β-estradiol decrease and a more rapid LH increase in mares

被引：25
|
作者：
Ginther, O. J. [1 ,2 ]
Beg, M. A.
Gastal, E. L.
Gastal, M. O. [2 ]
Cooper, D. A. [2 ]
机构：
[1] Univ Wisconsin, Dept Pathobiol Sci, Sch Vet Med, Madison, WI 53706 USA
[2] Eutheria Fdn, Cross Plains, WI 53528 USA
来源：
ANIMAL REPRODUCTION SCIENCE | 2009年 / 114卷 / 1-3期
关键词：
Estradiol; hcG; LH; Mares; Ovulation; GNRH ANTAGONIST; HORMONES; ESTRADIOL; FOLLICLE;
D O I：
10.1016/j.anireprosci.2008.08.026
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
The effect of treatment with an ovulation-inducing dose of human chorionic gonadotropin (hCG) on 17 beta-estradiol (estradiol) and LH concentrations was studied in mares. In Experiment 1, treatment with hCG resulted in ovulation in approximately 48 h. The LH surge centralized to ovulation and the preovulatory decline in estradiol were not different between hCG-treated (n = 15) and control (n = 13) groups. In Experiment 2, concentrations of hCG decreased 92% between I and 48 h after hCG treatment, estradiol decreased (P < 0.003) within 6 h, and LH increased at a greater (P < 0.02) rate after 12 h (n = 14). Results indicated: (1) hCG induced a decrease in estradiol and a subsequent greater rate of increase in LH and (2) when centralized to ovulation, the endogenous LH surge and the estradiol decrease were similar between hCG-treated and control groups. (c) 2008 Elsevier B.V. All rights reserved.
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页码：311 / 317
页数：7
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