Treatment of Alzheimer and other tauopathies by inhibition of neurofibrillary degeneration

被引:0
|
作者
Iqbal, K [1 ]
Grundke-Iqbal, I [1 ]
机构
[1] New York State Inst Basic Res Dev Disabil, Staten Isl, NY 10314 USA
关键词
D O I
10.1016/S0197-4580(04)80098-8
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:S30 / S30
页数:1
相关论文
共 50 条
  • [31] Concomitant TAR-DNA-binding in Alzheimer disease and protein 43 pathology is present corticobasal degeneration but not in other tauopathies
    Uryu, Kunihiro
    Nakashima-Yasuda, Hanae
    Forman, Mark S.
    Kwong, Linda K.
    Clark, Christopher M.
    Grossman, Murray
    Miller, Bruce L.
    Kretzschmar, Hans A.
    Lee, Virginia M. -Y.
    Trojanowski, John Q.
    Neumann, Manuela
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2008, 67 (06): : 555 - 564
  • [32] Selective neurofibrillary degeneration of the hippocampal CA2 sector is associated with four-repeat tauopathies
    Ishizawa, T
    Ko, LW
    Cookson, N
    Davies, P
    Espinoza, M
    Dickson, DW
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2002, 61 (12): : 1040 - 1047
  • [33] Whole CNS Human Tau Knockdown for the Potential Treatment of Alzheimer's Disease and Other Tauopathies
    Zeitler, Bryan J.
    Marlen, Kimberly
    Ojala, David
    Ledeboer, Annemarie
    Yu, Qi
    Pan, Yonghua
    Cisbani, Giulia
    Peters, Finn
    Melis, Chiara
    Tiffany, Matthew R.
    Mueller, Sarah
    Kennard, Kenneth
    Dunn, Patrick
    Hoang-Oanh Nguyen
    Hung Tran
    Meyer, Kathleen
    Pooler, Amy
    MOLECULAR THERAPY, 2024, 32 (04) : 535 - 535
  • [34] Significance and mechanism of alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion
    Khalid Iqbal
    Alejandra del C. Alonso
    Ezzat El-Akkad
    Cheng-Xin Gong
    Niloufar Haque
    Sabiha Khatoon
    Jin-Jing Pei
    Ichiro Tsujio
    Jian-Zhi Wang
    Inge Grundke-Iqbal
    Journal of Molecular Neuroscience, 2002, 19 : 95 - 99
  • [35] Association of ATP synthase α-chain with neurofibrillary degeneration in Alzheimer's disease
    Sergeant, N
    Wattez, A
    Galván-Valencia, M
    Ghestem, A
    David, JP
    Lemoine, J
    Sautière, PE
    Dachary, J
    Mazat, JP
    Michalski, JC
    Velours, J
    Mena-López, R
    Delacourte, A
    NEUROSCIENCE, 2003, 117 (02) : 293 - 303
  • [36] Tau phosphosignatures discriminate Alzheimer Disease from other tauopathies
    Seyfried, Nicholas
    Dammer, Eric
    Ren, Rujing
    Gearing, Marla
    Duc Duong
    Lah, James
    Levey, Allan
    FASEB JOURNAL, 2015, 29
  • [37] Alzheimer neurofibrillary degeneration - Therapeutic targets and high-throughput assays
    Iqbal, K
    Alonso, AD
    El-Akkad, E
    Gong, CX
    Haque, N
    Khatoon, S
    Pei, JJ
    Tanimukai, H
    Tsujio, I
    Wang, JZ
    Grundke-Iqbal, I
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2003, 20 (03) : 425 - 429
  • [38] The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease - Reply
    Delacourte, A
    NEUROLOGY, 2000, 54 (02) : 538 - 538
  • [39] ALZHEIMER-DISEASE - FROM ABNORMAL PHOSPHORYLATION OF TAU TO NEUROFIBRILLARY DEGENERATION
    IQBAL, K
    ALONSO, AD
    GONG, CX
    KHATOON, S
    PEI, JJ
    WANG, JZ
    GRUNDKEIQBAL, I
    NEUROBIOLOGY OF AGING, 1994, 15 : S31 - S31
  • [40] Apoptotic mechanisms isms in Alzheimer neurofibrillary degeneration generation: cause or effect?
    Dickson, DW
    JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (01): : 23 - 27