Comprehensive suppression of the renin-angiotensin-aldosterone system in chronic kidney disease: Covering all of the bases

被引：5
|
作者：
Weinberger, M. H.
Luft, F. C.
机构：
[1] Indiana Univ, Med Ctr, Dept Med, Indianapolis, IN 46202 USA
[2] Humboldt Univ, Max Delbrook Ctr, Franz Volhard Clin, Med Fac Charite,Bephrol Hypertens Sect, D-1086 Berlin, Germany
来源：
KIDNEY INTERNATIONAL | 2006年 / 70卷 / 12期
关键词：
D O I：
10.1038/sj.ki.5002007
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Reducing proteinuria and blood pressure in chronic kidney disease (CKD) decreases rate of progression. Inhibition of the renin angiotensin system by angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers is beneficial in reducing proteinuria but incomplete in suppressing aldosterone production and its renal effects. Adding aldosterone receptor blockers to these other agents may further halt the progression of CKD.
引用
收藏
页码：2051 / 2053
页数：4
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