Access to 5H-benzo[a]carbazol-6-ols and benzo[6,7]cyclohepta[1,2-b]indol-6-olsviarhodium-catalyzed C-H activation/carbenoid insertion/aldol-type cyclization

被引：22

作者：

Yuan, Yumeng ^{[1
]}

Guo, Xiemin ^{[1
]}

Zhang, Xiaofeng ^{[1
]}

Li, Buhong ^{[2
]}

Huang, Qiufeng ^{[1
]}

机构：

[1] Fujian Normal Univ, Coll Chem & Mat Sci, Fujian Key Lab Polymer Mat, Fuzhou 350007, Fujian, Peoples R China

[2] Fujian Normal Univ, Fujian Key Lab Photon Technol, MOE Key Lab Optoelect Sci & Technol Med, Fuzhou 350007, Fujian, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2020年 / 7卷 / 20期

关键词：

ONE-POT SYNTHESIS; DIAZO-COMPOUNDS; OXIDATIVE ANNULATION; BOND ACTIVATION; DIRECTING GROUP; FUNCTIONALIZATION; INDOLES; OLEFINATION; CARBONYLATION; 2-ARYLINDOLES;

D O I：

10.1039/d0qo00820f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The rhodium-catalyzed mono-orthoC-H activation/carbenoid insertion/aldol-type cyclization of 3-aldehyde-2-phenyl-1H-indoles with diazo compounds has been developed. This method provides a novel approach to 5H-benzo[a]carbazol-6-ols and benzo[6,7]cyclohepta[1,2-b]indol-6-ols with a broad range of substrate scope in an air atmosphere. In addition, the synthetic potentialities of the developed approach are demonstrated by gram scale and versatile late-stage transformations.

引用

页码：3146 / 3159

页数：14

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