A simple, rapid and efficient protocol for the synthesis of methylthiomethyl esters under Swern oxidation conditions

被引:22
|
作者
Jadhav, Sunil B. [1 ]
Ghosh, Usha [1 ]
机构
[1] Nicholas Piramal Res Ctr, Dept Med Chem, Bombay 400063, Maharashtra, India
关键词
Swern oxidation; carboxylic acids; methylthiomethyl esters;
D O I
10.1016/j.tetlet.2007.02.036
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A rapid, mild and high yielding method for the synthesis of methylthiomethyl esters is reported from the corresponding aliphatic, aromatic and unsaturated carboxylic acids under Swern oxidation conditions using dimethylsulfoxide, oxalyl chloride and triethylamine at low temperature. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2485 / 2487
页数:3
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