Neural Control of Walking in People with Parkinsonism

被引：117

作者：

Peterson, D. S. ^{[1
,2
]}

Horak, F. B. ^{[1
,2
]}

机构：

[1] Vet Affairs Portland Hlth Care Syst VAPORHCS, Portland, OR USA

[2] Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

来源：

PHYSIOLOGY | 2016年 / 31卷 / 02期

基金：

美国国家卫生研究院;

关键词：

POSTURAL MUSCLE TONE; BASAL-GANGLIA; BRAIN-STEM; BILATERAL COORDINATION; GAIT TASKS; DOPAMINERGIC MEDICATION; INTERLIMB COORDINATION; LATERAL PREMOTOR; SUPPORT SURFACE; DISEASE;

D O I：

10.1152/physiol.00034.2015

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

People with Parkinson's disease exhibit debilitating gait impairments, including gait slowness, increased step variability, and poor postural control. A widespread supraspinal locomotor network including the cortex, cerebellum, basal ganglia, and brain stem contributes to the control of human locomotion, and altered activity of these structures underlies gait dysfunction due to Parkinson's disease.

引用

页码：95 / 107

页数：13

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