Transition-Metal-Mediated Reactions for Csp2-F Bond Construction: The State of Play

被引：95

作者：

Brown, John M. ^{[1
]}

Gouverneur, Veronique ^{[1
]}

机构：

[1] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 46期

关键词：

alkenes; arenes; homogeneous catalysis; fluorine; transition metals; FORMING REDUCTIVE ELIMINATION; ARYLPALLADIUM(II) HALIDE-COMPLEXES; POSITRON-EMISSION-TOMOGRAPHY; PALLADIUM(IV) COMPLEXES; CESIUM FLUOROXYSULFATE; ACETYL HYPOFLUORITE; ARYLBORONIC ACIDS; ARYL FLUORIDES; C-O; FLUORINATION;

D O I：

10.1002/anie.200902121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It's a rate thing: Crucial conceptual advances have allowed for the development of a Pd-mediated pathway to Caryl-F by using either electrophilic (right) or nucleophilic (left) fluorinating reagents. Of significance is the recognition that PdIV intermediates reduce the barrier to C-F reductive elimination and the use of an ancillary bulky ligand to force reductive elimination from a 14-electron PdII complex. © 2009 Wiley-VCH Verlag GmbH &. Co. KGaA.

引用

页码：8610 / 8614

页数：5

共 50 条

[21] Transition-Metal-Mediated Cascade Reactions: C,C-Dicyclopropylmethylamines by Way of Double C,C-σ-Bond Insertion into Bicyclobutanes
1600, American Chemical Society (125):
[22] Transition-metal-mediated cascade reactions:: C,C-dicyclopropylmethylamines by way of double C,C-σ-bond insertion into bicyclobutanes
Wipf, P
Stephenson, CRJ
Okumura, K
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (48) : 14694 - 14695
[23] AN UNUSUAL TRANSITION-METAL-MEDIATED [2+2+2] CYCLIZATION OF FUNCTIONALIZED ALKENES
CHENG, MH
LIN, SH
CHOW, JF
LEE, GH
PENG, SM
LIU, RS
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (09) : 757 - 758
[24] 2-furyl phosphines as ligands for transition-metal-mediated organic synthesis
Andersen, NG
Keay, BA
CHEMICAL REVIEWS, 2001, 101 (04) : 997 - 1030
[25] TRANSITION-METAL-MEDIATED PHOSPHORUS CARBON BOND-CLEAVAGE AND ITS RELEVANCE TO HOMOGENEOUS CATALYST DEACTIVATION
GARROU, PE
CHEMICAL REVIEWS, 1985, 85 (03) : 171 - 185
[26] Transition-metal-mediated C-C bond activation: Recent advances and its applications in organic synthesis
Verma, Nand Lal
Kumar, Mohit
Sharma, Deepa
Jaipal
Kumar, Shilendra
Rathore, Nisha
Jaiswar, Gautam
RESULTS IN CHEMISTRY, 2023, 6
[27] Special feature section: Transition-metal-mediated C-C and C-N bond formation
Lennon, Ian C.
Bhatia, Ashok V.
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2008, 12 (03) : 467 - 467
[28] SYNTHETIC STUDIES ON TRANSITION-METAL-MEDIATED HIGHER-ORDER CYCLOADDITION REACTIONS - HIGHLY STEREOSELECTIVE CONSTRUCTION OF SUBSTITUTED BICYCLO[4.4.1]UNDECANE SYSTEMS
RIGBY, JH
ATEEQ, HS
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (17) : 6442 - 6443
[29] Synthetic studies on transition-metal-mediated higher order cycloaddition reactions. Highly stereoselective construction of substituted bicyclo[4.4.1[undecane systems
1600, (112):
[30] Preparation, properties, and reactions of metal-containing heterocycles .95. Transition-metal-mediated cyclocotrimerization of selenophosphinites with activated alkynes
Lindner, E
Bosch, E
Fawzi, R
Steimann, M
Mayer, HA
Gierling, K
CHEMISCHE BERICHTE, 1996, 129 (08) : 945 - 951

← 1 2 3 4 5 →