Effects of isothiocyanates on tumor necrosis factor-α production by J774A.1 (BALB/c macrophage) cells

被引：3

作者：

Ohta, Y ^{[1
]}

Yamaki, K

Osawa, T

Kawakishi, S

机构：

[1] Hiroshima Prefectural Food Technol Res Ctr, Minami Ku, Hiroshima 7320816, Japan

[2] Natl Agr Res Ctr Tohoku Reg, Fukushima 9602156, Japan

[3] Nagoya Univ, Grad Sch Bioagr Sci, Chikusa Ku, Nagoya, Aichi 4648601, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2004年 / 68卷 / 06期

关键词：

isothiocyanate; tumor necrosis factor-alpha; macrophage; priming effect; inhibitory effect;

D O I：

10.1271/bbb.68.1375

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effects of isothiocyanates (ITCs) on tumor necrosis factor-alpha (TNF-alpha) production by the J774A.1 mouse macrophage cell line stimulated with lipopolysaccharide (LPS) were examined. Some individual ITCs examined showed a priming effect, which was expressed as pre-activation, but also inhibited the production of TNF-a with concomitant stimulation by LPS, as a triggering stimulant of TNF production. These results suggest that ITCs exert opposing activities that can enhance or inhibit the host defense system.

引用

页码：1375 / 1378

页数：4

共 50 条

[1] Preventive effects of a traditional Chinese medicine (Sho-saiko-to) on endotoxin-induced cytotoxicity and tumor necrosis factor-α production in J774A.1 cells
Sakaguchi, S
Furusawa, S
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2004, 27 (09) : 1468 - 1470
[2] Synergistic effect of Staphylococcus aureus and LPS on silica-induced tumor necrosis factor production in macrophage cell line J774A.1
Lee, DH
Park, BJ
Lee, MS
Choi, JB
Kim, JK
Park, JH
Park, JC
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 16 (01) : 136 - 140
[3] The effect of lead on nitric oxide production in stimulated (J774A.1) macrophage cells.
Ikajddi, A
Soliman, KFA
FASEB JOURNAL, 1998, 12 (04): : A463 - A463
[4] Interferon-γ- and lipopolysaccharide-induced tumor necrosis factor-α is required for nitric oxide production:: Tumor necrosis factor-α and nitric oxide are independently involved in the killing of Mycobacterium microti in interferon-γ- and lipopolysaccharide-treated J774A.1 cells
Majumdar, S
Gupta, R
Dogra, N
FOLIA MICROBIOLOGICA, 2000, 45 (05) : 457 - 463
[5] Interferon-γ- and lipopolysaccharide-induced tumor necrosis factor-α is required for nitric oxide production: Tumor necrosis factor-α and nitric oxide are independently involved in the killing ofMycobacterium microti in interferon-γ-and lipopolysaccharide-treated J774A.1 cells
S. Majumdar
R. Gupta
N. Dogra
Folia Microbiologica, 2000, 45 : 457 - 463
[6] The effect of oligosaccharides on the production of tumor necrosis factor-α by macrophage-like cell line J774/JA-4
Momotani, E
Watanabe, S
Yoshihara, K
Amano, F
JOURNAL OF VETERINARY MEDICAL SCIENCE, 1998, 60 (04): : 519 - 522
[7] Inhibitory effects of cassia oil on LPS-stimulated murine macrophage J774A.1 cells
Chinjarernpan, Pannee
Itthipanichpong, Chandhanee
Limpanasithikul, Wacharee
ACTA PHARMACOLOGICA SINICA, 2013, 34 : 82 - 82
[8] Nerve growth factor modulates Fc gamma receptor expression on murine macrophage J774A.1 cells
Susaki, Y
Tanaka, A
Honda, E
Matsuda, H
JOURNAL OF VETERINARY MEDICAL SCIENCE, 1998, 60 (01): : 87 - 91
[9] Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin
Carballo, E
Lai, WS
Blackshear, PJ
SCIENCE, 1998, 281 (5379) : 1001 - 1005
[10] Garlic (Allium sativum) Stimulates Lipopolysaccharide-induced Tumor Necrosis Factor-alpha Production from J774A.1 Murine Macrophages
Sung, Jessica
Harfouche, Youssef
De la Cruz, Melissa
Zamora, Martha P.
Liu, Yan
Rego, James A.
Buckley, Nancy E.
PHYTOTHERAPY RESEARCH, 2015, 29 (02) : 288 - 294

← 1 2 3 4 5 →