Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

被引：18
|
作者：
Pinheiro, Eduardo A. A. [1 ]
Carvalho, Josiwander M. [1 ]
dos Santos, Diellem C. P. [1 ]
Feitosa, Andre O. [1 ]
Marinho, Patricia S. B. [1 ]
Guilhon, Giselle Maria S. P. [1 ]
Santos, Lourivaldo S. [1 ]
de Souza, Afonso L. D. [2 ]
Marinho, Andrey M. R. [1 ]
机构：
[1] Fed Univ Para, Fac Quim, BR-66075110 Belem, Para, Brazil
[2] Univ Fed Amazonas, Dept Quim, BR-69077000 Manaus, Amazonas, Brazil
来源：
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS | 2013年 / 85卷 / 04期
关键词：
chemical constituents; antimicrobial assay; Aspergillus; Bauhinia guianensis; FUNGUS;
D O I：
10.1590/0001-3765201395512
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.
引用
收藏
页码：1247 / 1252
页数：6
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