Lipid metabolism and transport define longevity of the yeast Saccharomyces cerevisiae

被引：8
|
作者：
Mitrofanova, Darya [1 ]
Dakik, Pamela [1 ]
McAuley, Melissa [1 ]
Medkour, Younes [1 ]
Mohammad, Karamat [1 ]
Titorenko, Vladimir, I [1 ]
机构：
[1] Concordia Univ, Dept Biol, 7141 Sherbrooke St West,Sci Pavil,Off SP-501-13, Montreal, PQ H4B 1R6, Canada
来源：
FRONTIERS IN BIOSCIENCE-LANDMARK | 2018年 / 23卷
基金：
加拿大自然科学与工程研究理事会;
关键词：
Aging; Longevity; Mechanisms; Lipid metabolism; Review; CHRONOLOGICAL LIFE-SPAN; PHOSPHOSPHINGOLIPID PHOSPHOLIPASE-C; DROPLET-ORGANELLE INTERACTIONS; OXIDATIVE STRESS SENSITIVITY; PLANT DEFENSIN-SENSITIVITY; FATTY-ACID-METABOLISM; CALORIC RESTRICTION; MITOCHONDRIAL DYSFUNCTION; SPHINGOLIPID METABOLISM; ENDOPLASMIC-RETICULUM;
D O I：
10.2741/4638
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Emergent evidence indicates that certain aspects of lipid synthesis, degradation and interorganellar transport play essential roles in modulating the pace of cellular aging in the budding yeast Saccharomyces cerevisiae. The molecular mechanisms underlying the vital roles of lipid metabolism and transport in defining yeast longevity have begun to emerge. The scope of this review is to critically analyze recent progress in understanding such mechanisms.
引用
收藏
页码：1166 / 1194
页数：29
相关论文
共 50 条
  • [41] GENETIC-REGULATION OF METABOLISM IN YEAST SACCHAROMYCES-CEREVISIAE
    RYTKA, J
    POSTEPY BIOCHEMII, 1978, 24 (02) : 151 - 176
  • [42] Vesicular Transport of Extracellular Acid Phosphatases in Yeast Saccharomyces cerevisiae
    E. I. Blinnikova
    F. L. Mirjuschenko
    Yu. A. Shabalin
    S. N. Egorov
    Biochemistry (Moscow), 2002, 67 : 485 - 490
  • [43] Vesicular transport of extracellular acid phosphatases in yeast Saccharomyces cerevisiae
    Blinnikova, EI
    Mirjuschenko, FL
    Shabalin, YA
    Egorov, SN
    BIOCHEMISTRY-MOSCOW, 2002, 67 (04) : 485 - 490
  • [44] Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae
    Guo, Zhong-peng
    Khoomrung, Sakda
    Nielsen, Jens
    Olsson, Lisbeth
    BIOTECHNOLOGY FOR BIOFUELS, 2018, 11
  • [45] Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae
    Zhong-peng Guo
    Sakda Khoomrung
    Jens Nielsen
    Lisbeth Olsson
    Biotechnology for Biofuels, 11
  • [46] STUDIES ON BEHAVIOUR OF 3H-OCTIN-(2) ACID(1) IN LIPID METABOLISM OF YEAST SACCHAROMYCES CEREVISIAE
    KASANG, G
    ARZNEIMITTEL-FORSCHUNG, 1968, 18 (03): : 378 - &
  • [47] EFFECTS OF TRIFLUPERIDOL ON LIPID-METABOLISM OF SACCHAROMYCES-CEREVISIAE
    SOBUS, MT
    FEDERATION PROCEEDINGS, 1976, 35 (07) : 1699 - 1699
  • [48] Design and application of a kinetic model of lipid metabolism in Saccharomyces cerevisiae
    Mishra, Shekhar
    Wang, Ziyu
    Volk, Michael J.
    Zhao, Huimin
    METABOLIC ENGINEERING, 2023, 75 : 12 - 18
  • [49] Effect of extracellular phospholipids on the growth and lipid metabolism of Saccharomyces cerevisiae
    Ohta, A
    Oh, YJ
    Nakamura, H
    Takagi, M
    FASEB JOURNAL, 1998, 12 (08): : A1287 - A1287
  • [50] Membrane-associated lipid transfer activity in the yeast Saccharomyces cerevisiae
    Tahotna, D
    Hapala, I
    Flekl, W
    Daum, G
    CHEMICKE LISTY, 1996, 90 (09): : 633 - 634
12345