From aziridines to oxazolines and thiazolines: The heterocyclic route to thiangazole

被引：0
|
作者：
Wipf, P
Venkatraman, S
机构：
来源：
SYNLETT | 1997年 / 01期
关键词：
Staudinger reaction; alpha-methyl serine; alpha-methyl cysteine; thiolysis; Burgess reagent;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Since its isolation in 1991, the polyazole natural product thiangazole has become a popular target for total synthesis due to its challenging array of heterocyclic segments and its reported potent antiviral activity. The synthetic activity toward thiangazole is reviewed and a novel approach that takes advantage of aziridine and oxazoline intermediates en route to thiazolines is presented.
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页码：1 / &
页数：11
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