Diastereoselective zinc-catalyzed conjugate addition of alkynes

被引：36
|
作者：
Knöpfel, TF [1 ]
Boyall, D [1 ]
Carreira, EM [1 ]
机构：
[1] ETH Honggerberg, Organ Chem Lab, CH-8093 Zurich, Switzerland
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 13期
关键词：
D O I：
10.1021/ol0491585
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] The conjugate addition of in situ generated zinc alkynylides is reported. The use of chiral, ephedrine derived acceptors provides access to enantiomerically enriched beta-alkynyl acids in good yields.
引用
收藏
页码：2281 / 2283
页数：3
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