Is Sentinel Lymph Node Biopsy Necessary in Patients Undergoing Prophylactic Mastectomy? A Systematic Review and Meta-Analysis

被引:16
|
作者
Nagaraja, Vinayak [1 ]
Edirimanne, Senarath [1 ]
Eslick, Guy D. [1 ]
机构
[1] Sydney Med Sch Nepean, Discipline Surg, Whiteley Martin Res Ctr, Penrith, NSW, Australia
来源
BREAST JOURNAL | 2016年 / 22卷 / 02期
关键词
breast cancer; prophylactic mastectomy; sentinel lymph node biopsy; UNILATERAL BREAST-CANCER; CONTRALATERAL BREAST; DRAINAGE PATTERNS; FAMILY-HISTORY; HIGH-RISK; WOMEN; EFFICACY; BRCA1; PREDICTORS; INCREASE;
D O I
10.1111/tbj.12549
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The gain by performing sentinel lymph node biopsy (SLNB) during prophylactic mastectomy (PM) is debatable, and we performed a meta-analysis of existing literature to evaluate that the role of SLNB in subjects undergoing PM. A systematic search was conducted using MEDLINE, PubMed, EMBASE, Current Contents Connect, Cochrane library, Google Scholar, Science Direct, and Web of Science. The search identified 11 relevant articles reporting on patients who underwent SLNB at the time of PM. Data were abstracted from each study and used to calculate a pooled odds ratio (OR) and 95% confidence interval (95% CI). We included 14 studies comprising of 2,708 prophylactic mastectomies. Among 2,708 prophylactic mastectomies, the frequency of occult invasive cancer (51 cases) was 1.8% and the rate of positive SLNs (33 cases) was 1.2%. In 25 invasive cancers at the time of PM were found to have negative SLNs which avoided axillary lymph node dissection (ALND). In seven cases with positive SLNBs were found not to have invasive cancer at the time of PM and needed a subsequent ALND. Most of the patients with positive SLNs had locally advanced disease in the contralateral breast. SLNB may be suitable for patients with ipsilateral, locally advanced breast cancer and is not recommend for all patients undergoing PM.
引用
收藏
页码:158 / 165
页数:8
相关论文
共 50 条
  • [41] The Role of Sentinel Lymph Node Biopsy in Cutaneous Head and Neck Melanoma: A Systematic Review and Meta-Analysis
    Johnston, E.
    Taylor, S.
    Bannon, F.
    McAllister, S.
    BRITISH JOURNAL OF SURGERY, 2021, 108
  • [42] The Role of Sentinel Lymph Node Biopsy in the Management of Merkel Cell Carcinoma: A Systematic Review and Meta-analysis
    Kanakopoulos, Dimitrios
    Lacey, Hester
    Payne, Anna
    Houlihan, Maria
    Riyat, Harjoat
    Wheelan, Rhys
    Cubitt, Jonathan
    Totty, Joshua P.
    PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, 2024, 12 (04)
  • [43] Impact of Axillary Lymph Node Dissection and Sentinel Lymph Node Biopsy on Upper Limb Morbidity in Breast Cancer Patients A Systematic Review and Meta-Analysis
    Che Bakri, Nur Amalina
    Kwasnicki, Richard M.
    Khan, Naairah
    Ghandour, Omar
    Lee, Alice
    Grant, Yasmin
    Dawidziuk, Aleksander
    Darzi, Ara
    Ashrafian, Hutan
    Leff, Daniel R.
    ANNALS OF SURGERY, 2023, 277 (04) : 572 - 580
  • [44] Utilization of Sentinel Lymph Node Biopsy in Patients with Ductal Carcinoma In Situ Undergoing Mastectomy
    Shah, Dhruvil R.
    Canter, Robert J.
    Khatri, Vijay P.
    Bold, Richard J.
    Yang, Anthony D.
    Martinez, Steve R.
    ANNALS OF SURGICAL ONCOLOGY, 2013, 20 (01) : 24 - 30
  • [45] Utilization of Sentinel Lymph Node Biopsy in Patients with Ductal Carcinoma In Situ Undergoing Mastectomy
    Shah, D. R.
    Canter, R. J.
    Khatri, V. P.
    Bold, R. J.
    Martinez, S. R.
    ANNALS OF SURGICAL ONCOLOGY, 2012, 19 : S41 - S41
  • [46] Utilization of Sentinel Lymph Node Biopsy in Patients with Ductal Carcinoma In Situ Undergoing Mastectomy
    Dhruvil R. Shah
    Robert J. Canter
    Vijay P. Khatri
    Richard J. Bold
    Anthony D. Yang
    Steve R. Martinez
    Annals of Surgical Oncology, 2013, 20 : 24 - 30
  • [47] Enlarged para-sentinel lymph node dissection is not necessary in breast cancer patients undergoing sentinel lymph node biopsy
    Li, Xiaoyan
    Kong, Xiaoli
    Chen, Sisi
    Jiang, Liyu
    Ma, Tingting
    Yang, Qifeng
    BREAST JOURNAL, 2019, 25 (05): : 1025 - 1028
  • [48] Lymphatic Mapping and Sentinel Lymph Node Biopsy in Patients With Melanoma: A Meta-Analysis
    Valsecchi, Matias E.
    Silbermins, Damian
    de Rosa, Nicole
    Wong, Sandra L.
    Lyman, Gary H.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (11) : 1479 - 1487
  • [49] The role of sentinel lymph node biopsy in select sarcoma patients: a meta-analysis
    Wright, Sharee
    Armeson, Kent
    Hill, Elizabeth G.
    Streck, Christian
    Leddy, Lee
    Cole, David
    Esnaola, Nestor
    Camp, E. Ramsay
    AMERICAN JOURNAL OF SURGERY, 2012, 204 (04): : 428 - 433
  • [50] Sentinel lymph node biopsy in cervical cancer: A meta-analysis
    Wu, Yibo
    Li, Zeming
    Wu, Haiyan
    Yu, Jinjin
    MOLECULAR AND CLINICAL ONCOLOGY, 2013, 1 (06) : 1025 - 1030