Advancing biological imaging with multi-spectral optoacoustic tomography (MSOT)

被引：0
|
作者：
Ntziachristos, V. [1 ]
机构：
[1] Tech Univ Munich, IBMI, D-85764 Neuherberg, Germany
来源：
2009 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, VOLS 1 AND 2 | 2009年
关键词：
multispectral optoacoustic tomography; molecular imaging; fluorescence imaging;
D O I：
10.1109/ISBI.2009.5193276
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Multi-spectral optoacoustic tomography (MSOT) is an imaging method that can resolve fluorochromes and other reporter molecules with high sensitivity and specificity deep inside live animals and tissues. The method can penetrate for several millimeters to centimeters in tissues and offers resolutions in the 30 - 100 micron range. We discuss advances with technical implementation and in-vivo imaging applications ranging from mesoscopic imaging of drosophila and adult zebrafish to imaging various cellular functions in mice. MSOT comes with significant potential to shift the paradigm of biological imaging and become a method of choice in basic and drug discovery and in several clinical applications.
引用
收藏
页码：1202 / 1202
页数：1
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