On global stability of an HIV pathogenesis model with cure rate

被引:4
|
作者
Muroya, Yoshiaki [1 ]
Enatsu, Yoichi [2 ]
机构
[1] Waseda Univ, Dept Math, Shinjuku Ku, Tokyo 1698555, Japan
[2] Univ Tokyo, Grad Sch Math Sci, Meguro Ku, Tokyo 1538914, Japan
基金
日本学术振兴会;
关键词
HIV pathogenesis model; global asymptotic stability; Lyapunov function; monotone iteration; CD4(+) T-CELLS; INFECTION; DYNAMICS; DELAY;
D O I
10.1002/mma.3334
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
In this paper, applying both Lyapunov function techniques and monotone iterative techniques, we establish new sufficient conditions under which the infected equilibrium of an HIV pathogenesis model with cure rate is globally asymptotically stable. By giving an explicit expression for eventual lower bound of the concentration of susceptible CD4(+) T cells, we establish an affirmative partial answer to the numerical simulations investigated in the recent paper [Liu, Wang, Hu and Ma, Global stability of an HIV pathogenesis model with cure rate, Nonlinear Analysis RWA (2011) 12: 2947-2961]. Our monotone iterative techniques are applicable for the small and large growth rate in logistic functions for the proliferation rate of healthy and infected CD4(+) T cells. Copyright (C) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:4001 / 4018
页数:18
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