Synthesis of the sialic acid (-)-KDN and certain epimers from (-)-3-dehydroshikimic acid or (-)-quinic acid

被引：15
|
作者：
Banwell, MG [1 ]
Hungerford, NL [1 ]
Jolliffe, KA [1 ]
机构：
[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 16期
关键词：
D O I：
10.1021/ol049048y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
(-)-3-Dehydroshikimic acid (3-DHS, 4), a C-7-building block now available in large quantity from corn syrup, has been converted into the sialic acid (-)-KDN (3) as well as its C-7- and C-8-epimers. (-)-Quinic acid can be used for the same purpose.
引用
收藏
页码：2737 / 2740
页数：4
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