SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL AZODERIVATIVES

被引:0
|
作者
Rau, Gabriela [1 ]
Mogosanu, George-Dan [2 ]
Stanciulescu, Camelia Elena
机构
[1] Univ Med & Pharm Craiova, Fac Pharm, Dept Organ Chem & Med Chem, Craiova 200349, Romania
[2] Univ Med & Pharm Craiova, Fac Pharm, Dept Pharmacognosy & Phytotherapy, Craiova 200349, Romania
关键词
azoderivatives; synthesis;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The paper presents 15 novel azoderivatives, obtained by the condensation of 2-methyl-N-chloroacetylaniline or 2-ethoxy-N-chloroacetylaniline with 4-(phenylazo) phenols 4'-substituted or not, or with 4-hydroxy4'-(phenylazo) biphenyls 4 ''-substituted or not, These new compounds have been characterized using physical methods (UV-Vis, IR, (1)H-NMR and Mass Spectra). The molecular modelling of the chemical structures, concerning molecular descriptors for QSPR (Quantitative Structure Property Relationship), was performed with Hyperchem 6.0, MM+ (Molecular Mechanics) method, CODESSA and MOPAC 6.0 soft packages. The phytobiological activity (Triticum test) was determined for the novel azoderivatives.
引用
收藏
页码:648 / 658
页数:11
相关论文
共 50 条
  • [1] SYNTHESIS, PHYSICO-CHEMICAL CHARACTERISATION AND MESOMORPHIC PROPERTIES OF SOME NOVEL AZODERIVATIVES
    Rau, Gabriela
    Mogosanu, George Dan
    Pisoschi, Catalina Gabriela
    Stanciulescu, Camelia Elena
    FARMACIA, 2014, 62 (03) : 486 - 495
  • [2] Synthesis of novel azoderivatives with mesomorphic properties
    Rau, Gabriela
    Iacobescu, Gabrieia
    Radu, Stelian
    Meltzer, Viorica
    Mogosanu, George Dan
    REVISTA DE CHIMIE, 2007, 58 (08): : 782 - 785
  • [3] NOVEL AZODERIVATIVES AS LIQUID CRYSTALS
    Rau, Gabriela
    Moanta, Anca
    Mogosanu, George-Dan
    REVUE ROUMAINE DE CHIMIE, 2008, 53 (12) : 1089 - 1095
  • [4] Synthesis and characterization of some novel aromatic polyimides
    Butt, MS
    Akhtar, Z
    Zafar-uz-Zaman, M
    Munir, A
    EUROPEAN POLYMER JOURNAL, 2005, 41 (07) : 1638 - 1646
  • [5] SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL POLY(NITROARYLATES)
    MANSOUR, ESME
    KANDIL, SH
    SOLIMAN, MEM
    IBRAHIM, M
    POLYMER INTERNATIONAL, 1992, 29 (01) : 61 - 68
  • [6] Synthesis and characterization of some novel tetrazole liquid crystals
    Tariq, Muhammad
    Hameed, Shahid
    Bechtold, Ivan H.
    Bortoluzzi, Adailton J.
    Merlo, Aloir A.
    JOURNAL OF MATERIALS CHEMISTRY C, 2013, 1 (35) : 5583 - 5593
  • [7] Synthesis and Characterization of Some Novel Dendritic Phenothiazine Derivatives
    Liu, Yuting
    Liu, Kai
    Yin, Dawei
    Yang, Lisha
    Dang, Yang
    Yang, Lan
    Zou, Qian
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 55 (04) : 554 - 558
  • [8] Synthesis and characterization of some novel bis-thiazoles
    Mahmoud, Huda K.
    Kassab, Refaie M.
    Gomha, Sobhi M.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (11) : 3157 - 3163
  • [9] Synthesis, characterization and biological evaluation of some novel fluoroquinolones
    Neelanjana Pandit
    Kamal Shah
    Neetu Agrawal
    Neeraj Upmanyu
    Sushant K. Shrivastava
    Pradeep Mishra
    Medicinal Chemistry Research, 2016, 25 : 843 - 851
  • [10] Synthesis and Characterization of Some Novel Dichromophoric Cyanine Dyes
    Nourmohammadian, Farahnaz
    Gholami, Mahnaz Davoudzadeh
    SYNTHETIC COMMUNICATIONS, 2009, 39 (11) : 1981 - 1991