Western Australian cigarette smokers have fewer small lung nodules than North Americans on CT screening for lung cancer

被引:1
|
作者
Murray, C. P. [1 ]
Wong, P. M. [2 ]
Louw, J. [1 ]
Waterer, G. W. [2 ]
机构
[1] Univ Western Australia, Royal Perth Hosp, Dept Intervent & Diagnost Radiol, Perth, WA 6009, Australia
[2] Univ Western Australia, Sch Med & Pharmacol, Perth, WA 6009, Australia
关键词
computed tomography; lung cancer; mass screening; DOSE SPIRAL CT; PULMONARY NODULES; BASE-LINE; POPULATION; 5-YEAR;
D O I
10.1111/j.1754-9485.2009.02037.x
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
P>To determine the prevalence of small lung nodules on low-dose helical computed tomography (CT) in a Western Australian cohort of asymptomatic long-term cigarette smokers and to compare this with a large, similarly derived cohort of North Americans from the Mayo Clinic Lung Cancer Screening Trial. Forty-nine asymptomatic long-term cigarette smokers of minimum age 50 years underwent a low-dose 64-slice helical CT of the lungs. Images were viewed on a soft copy reporting station with thin section axial and coronal images, maximum intensity projection images, and advanced image manipulation tools. The prevalence of all nodules was 39%, significantly lower than the Mayo Clinic cohort prevalence of 51% (P < 0.01, Fisher's exact test), despite the use of more advanced imaging technology and image manipulation designed to increase the sensitivity for nodules. The prevalence of small nodules in asymptomatic long-term cigarette smokers in Western Australia is high, though significantly less than that found in a large study in North America. The authors postulate this is due to the relatively low rates of mycobacterium tuberculosis and soil-derived fungal pulmonary infections in Western Australia, as well as a lower degree of urban air pollution.
引用
收藏
页码:339 / 344
页数:6
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