Immunobiology of solid organ transplantation

被引：0
|
作者：
Turvey, SE [1 ]
Wood, KJ [1 ]
机构：
[1] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg, Oxford OX3 9DU, England
来源：
INTERNATIONAL SURGERY | 1999年 / 84卷 / 04期
关键词：
immunobiology; transplantation; rejection; tolerance;
D O I：
暂无
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The field of organ transplantation is entering a very exciting phase in which tolerance induction may become a therapeutic possibility. The induction of tolerance would allow patients to enjoy the benefits of their transplanted organ without risking the mortality and morbidity associated with long-term pharmacological immunosuppression. In this review, we explore the immunobiology of solid organ transplantation, discussing the immunological mechanisms responsible for allograft rejection, and outlining the rational behind a range of successful experimental tolerance induction strategies.
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页码：279 / 290
页数：12
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