Facile synthesis of 4H-chromene derivatives via base-mediated annulation of ortho-hydroxychalcones and 2-bromoallyl sulfones

被引：19
|
作者：
Thadkapally, Srinivas [1 ]
Kunjachan, Athira C. [1 ]
Menon, Rajeev S. [1 ]
机构：
[1] CSIR Indian Inst Chem Technol, Med Chem & Pharmacol Div, Hyderabad 500007, Andhra Pradesh, India
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 12卷
关键词：
allenes; chromenes; cyclocondenzation; sulfones; vinylic substitution; 3-ALKYL ALLENOATES; EFFICIENT; CHROMENES; SALICYLALDEHYDES; CONSTRUCTION; 2H-CHROMENES; CYCLIZATION; METATHESIS; 1,2-DIONES; DISCOVERY;
D O I：
10.3762/bjoc.12.3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The cesium carbonate-mediated reaction of 2-bromoallyl sulfones and ortho-hydroxychalcones furnished 3-arylsulfonyl-4-Hchromene derivatives in 58-67% yield (18 examples). 2-Bromoallyl sulfones functioned as synthetic surrogates for allenyl sulfones in the reaction.
引用
收藏
页码：16 / 21
页数：6
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