The epidemiological and clinical characteristics of measles in Wenzhou, China, 2000-2010

被引：4
|
作者：
Xu, Z. W. [1 ,2 ]
Chen, Y. P. [1 ,2 ]
Yang, M. J. [1 ,2 ]
Li, W. C. [3 ]
Liu, Q. [1 ,2 ]
Lin, J. [1 ,2 ,4 ]
机构：
[1] Second Affiliated Hosp, Dept Pediat, Wenzhou, Peoples R China
[2] Wenzhou Med Coll, Yuying Childrens Hosp, Wenzhou, Peoples R China
[3] Wenzhou Municipal Ctr Dis Control & Prevent, Wenzhou, Peoples R China
[4] Mt Sinai Sch Med, Dept Pediat, New York, NY USA
来源：
EPIDEMIOLOGY AND INFECTION | 2014年 / 142卷 / 01期
关键词：
Epidemiology; infectious disease; measles (rubeola); VACCINATION CAMPAIGN; INFANTS; ELIMINATION; RISK; AGE; MORTALITY; OUTBREAK; PROGRESS; CHILDREN; EUROPE;
D O I：
10.1017/S0950268813000411
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This study examined the epidemiological and clinical characteristics of measles in Wenzhou, China. From 2000 to 2010, a total of 13271 measles cases were reported in Wenzhou, with epidemics occurring every 3-4 years. Forty-five per cent of the cases were aged <1 year and 272% were aged >14 years. Of 2262 hospitalized measles cases, 663% were diagnosed with pneumonia, and three cases died from respiratory failure. The number of measles cases of infants requiring hospitalization increased from birth to age 8 months and declined thereafter. Measurement of serum measles antibody levels in normal infants indicates that over 80% of infants in Wenzhou may be susceptible to measles by age 6 months. The existence of a sufficient pool of unvaccinated children and the decreased level of passively transferred measles antibodies in infants from vaccinated mothers contributed to the sustained transmission observed in Wenzhou.
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页码：20 / 27
页数：8
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