Aryloxyethylamines:: Binding at α7 nicotinic acetylcholine receptors

被引：7
|
作者：
Ragab, Hanan M.
Kim, Jin Sung
Dukat, Malgorzata
Navarro, Hernan
Glennon, Richard A.
机构：
[1] Virginia Commonwealth Univ, Sch Pharm, Dept Med Chem, Richmond, VA 23298 USA
[2] Res Triangle Inst, Ctr Organ & Med Chem, Res Triangle Pk, NC 27709 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 16期
关键词：
nicotinic receptors; AXPQ;
D O I：
10.1016/j.bmcl.2006.05.080
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Structure-affinity relationships for the binding of 3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine (AXPQ) at alpha 7 nACh receptors were investigated due to its close structural similarity to a known alpha 7 antagonist. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4283 / 4286
页数：4
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