Efficient one-pot synthesis of anti-HIV and anti-tumour β-carbolines

被引：43
|
作者：
Kusurkar, RS [1 ]
Goswami, SK [1 ]
机构：
[1] Univ Poona, Dept Chem, Pune 411007, Maharashtra, India
来源：
TETRAHEDRON | 2004年 / 60卷 / 25期
关键词：
harman; harmine; beta-carboline; electrocyclisation; 1-aryl-beta-carboline;
D O I：
10.1016/j.tet.2004.04.079
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Thermal electrocyclisation of the azahexatriene system has been used as a key step for the synthesis of anti-HIV and anti-tumour compounds, harman, derivatives of harman and 1-aryl-beta-carbolines. A one-pot reaction sequence was used to furnish these compounds in good yield. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5315 / 5318
页数：4
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