Synthesis of Some New Heterocyclic Compounds Derived from 3-Formylchromones and Their Antimicrobial Evaluation

被引：16

作者：

Bari, A. ^{[1
,2
]}

Ali, S. S. ^{[2
]}

Kadi, A. ^{[1
]}

Hashmi, I. A. ^{[3
]}

Ng, S. W. ^{[4
]}

机构：

[1] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

[2] King Saud Univ, Coll Pharm, Res Ctr, Riyadh 11451, Saudi Arabia

[3] Univ Karachi, Dept Chem, Karachi 75270, Pakistan

[4] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2014年 / 49卷 / 12期

关键词：

3-formylchromone; pyranopyrones; antimicrobial activity; enzyme inhibitors; Knoevenagel-Cope reaction; pharmacophore; urease inhibitory; ACTIVE METHYLENE; INDUCTION; SERIES;

D O I：

10.1007/s10593-014-1424-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis and antimicrobial evaluation of a series of chromone-linked substituted heterocyclic derivatives is described. The condensation of 3-formylchromone with acetoacetamide under Knoevenagel-Cope reaction conditions was also explored, and the condensation with 4-hydroxy-6-methyl-2H-pyran-2-one constitutes a facile route to pyranopyrone fused systems. Most of the compounds exhibit good antimicrobial properties.

引用

页码：1723 / 1731

页数：9

共 50 条

[21] Synthesis of some new heterocyclic derivatives from aromatic carbonyl compounds and assessment of their antimicrobial activity
Al-Khazraji, Shaima I. C.
Chelebi, Noorhan A.
Bazzaz, Ayoub A.
JOURNAL OF POPULATION THERAPEUTICS AND CLINICAL PHARMACOLOGY, 2023, 30 (03): : E346 - E360
[22] Synthesis, Characterization and Antimicrobial Activities of Some New Heterocyclic Schiff Bases Derived from Thiocarbohydrazide
El-Mahdy, Kamelia M.
El-Kazak, Azza M.
Abdel-Megid, Mohamed
Seada, Magdy
Farouk, Osama
ACTA CHIMICA SLOVENICA, 2016, 63 (01) : 18 - 25
[23] Synthetic studies on the synthesis of some new fused heterocyclic compounds derived from 3,5-pyrazolidinedione
Khodairy, A.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2007, 54 (01) : 93 - 102
[24] Synthesis and Antimicrobial Activity of Some New Heterocyclic Schiff Bases Derived from 2-Amino-3-formylchromone
Ibrahim, Magdy A.
El-Mahdy, Kamelia M.
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2009, 184 (11) : 2945 - 2958
[25] One-pot synthesis of 3-formylchromones from bis-(trichloroxethyl) carbonate/DMF
Su, W. K.
Li, Z. H.
Zhao, L. Y.
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2007, 39 (05) : 495 - 502
[26] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME HETEROCYCLIC-COMPOUNDS
TRIVEDI, PB
UNDAVIA, NK
DAVE, AM
BHATT, KN
DESAI, NC
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1993, 32 (04): : 497 - 500
[27] SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NOVEL HETEROCYCLIC COMPOUNDS
Purohit, N. V.
Kadam, Kavita R.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 24 (02) : 193 - 198
[28] Synthesis, Characterization and Antimicrobial Evaluation of Some New Thioureas derived from 3-thiophenecarboxylic Acid
Badiceanu, Carmellina Daniela
Draghici, Constantin
Missir, Alexandru-Vasile
Chifiriuc, Mariana Carmen
Stecoza, Camelia Elena
REVISTA DE CHIMIE, 2014, 65 (02): : 160 - 163
[29] Synthesis of Some Heterocyclic Compounds Derived from Ortho- Carboxybenzaldehyde
Khder, Maysaa K. Sh Al-Mala
Al-Jawady, Moayed S.
EGYPTIAN JOURNAL OF CHEMISTRY, 2022, 65 (01): : 143 - 150
[30] Antimicrobial activity of some new heterocyclic [6.7.6] compounds
Limban, C.
Missir, A. -V.
Chirita, I. C.
Chifiriuc, M. C.
Caproiu, M. T.
Guta, R.
Morusciag, L.
Nuta, D. C.
Nitulescu, G. M.
FEBS JOURNAL, 2011, 278 : 438 - 438

← 1 2 3 4 5 →