Imaging of nonalcoholic fatty liver disease and its clinical utility

被引:34
|
作者
Chartampilas, Evangelos [1 ]
机构
[1] Bioclin Private Hosp, Thessaloniki, Greece
来源
HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM | 2018年 / 17卷 / 01期
关键词
Nonalcoholic fatty liver disease; Fat quantification; Liver fibrosis; Ultrasound; CT; MRI; MRspectroscopy; MR elastography; MAGNETIC-RESONANCE ELASTOGRAPHY; CONTRAST-ENHANCED CT; MACROVESICULAR HEPATIC STEATOSIS; ENERGY COMPUTED-TOMOGRAPHY; DIAGNOSTIC-ACCURACY; NONINVASIVE DIFFERENTIATION; STIFFNESS MEASUREMENT; FIBROSIS STAGE; ADULT PATIENTS; STEATOHEPATITIS;
D O I
10.1007/s42000-018-0012-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The prevalence of nonalcoholic fatty liver disease has been continuously rising over the last three decades and is projected to become the most common indication for liver transplantation in the near future. Its pathophysiology and complex interplay with diabetes and the metabolic syndrome are not as yet fully understood despite growing scientific interest and research. Modern imaging techniques offer significant assistance in this field by enabling the study of the liver noninvasively and evaluation of the degree of both steatosis and fibrosis, and even in attempting to diagnose the presence of inflammation (steatohepatitis). The derived measurements are highly precise, accurate and reproducible, performing better than biopsy in terms of quantification. In this article, these imaging techniques are overviewed and their performance regarding diagnosis, stratification and monitoring are evaluated. Their expanding role both in the research arena and in clinical practice along with their limitations is also discussed.
引用
收藏
页码:69 / 81
页数:13
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