Differential activation of atypical PKC and PKB by insulin in tissues of IRS-1 knockout mice

被引:0
|
作者
Sajan, MP
Standaert, ML
Miura, A
Kahn, CR
Farese, RV
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:A330 / A330
页数:1
相关论文
共 50 条
  • [21] ALTERNATIVE PATHWAY OF INSULIN SIGNALING IN MICE WITH TARGETED DISRUPTION OF THE IRS-1 GENE
    ARAKI, E
    LIPES, MA
    PATTI, ME
    BRUNING, JC
    HAAG, B
    JOHNSON, RS
    KAHN, CR
    NATURE, 1994, 372 (6502) : 186 - 190
  • [22] Differential subcellular signaling by IRS-1 and IRS-2
    Inoue, G
    Cheatham, B
    Kahn, CR
    DIABETES, 1997, 46 : 24 - 24
  • [23] Protein kinase C (PKC) β modulates serine phosphorylation of insulin receptor substrate-1 (IRS-1) -: Effect of overexpression of PKCβ on insulin signal transduction
    Ishizuka, T
    Kajita, K
    Natsume, Y
    Kawai, Y
    Kanoh, Y
    Miura, A
    Ishizawa, M
    Uno, Y
    Morita, H
    Yasuda, K
    ENDOCRINE RESEARCH, 2004, 30 (02) : 287 - 299
  • [24] Regulation of IRS-1 abilities to transmit insulin signals by the mTOR-dependent IRS-1 translocation
    Kawahara, J
    Haruta, T
    Hiratani, K
    Takano, A
    Uno, T
    Iwata, M
    Usui, I
    Kobayashi, M
    DIABETES, 2004, 53 : A311 - A311
  • [25] Insulin induces the interaction of IRS-1 with PKC-alpha and 14-3-3-epsilon
    Oriente, F
    Fiory, F
    Perfetti, A
    Trencia, A
    Punzo, C
    Ungaro, P
    Miele, C
    Beguinot, F
    Formisano, P
    DIABETES, 2004, 53 : A329 - A329
  • [26] Phosphorylation Codes in IRS-1 and IRS-2 Are Associated with the Activation/Inhibition of Insulin Canonical Signaling Pathways
    Baez, Anabel Martinez
    Ayala, Guadalupe
    Pedroza-Saavedra, Adolfo
    Gonzalez-Sanchez, Hilda M.
    Amparan, Lilia Chihu
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2024, 46 (01) : 634 - 649
  • [27] Diacylglcerol Activation of PKCθ Leads to Increased IRS-1 1101 Serine Phosphorylation and Skeletal Muscle Insulin Resistance in Obesity and Type 2 Diabetes
    Szendroedi, Julia
    Yoshimura, Toru
    Phielix, Esther
    Koliaki, Chrysi
    Marcucci, Melissa
    Zhang, Dongyan
    Jelenik, Tomas
    Herder, Christian
    Nowotny, Peter
    Shulman, Gerald I.
    Roden, Michael
    DIABETES, 2013, 62 : A460 - A460
  • [28] Atorvastatin induces profound insulin sensitization in Zucker lean rats by stimulating Akt/PKB phosphorylation independent of IRS-1
    Leung, N
    Stavar, L
    Sakaue, T
    Szeto, L
    Uffelman, K
    Adeli, K
    Fantus, G
    Lewis, G
    DIABETES, 2003, 52 : A330 - A330
  • [29] IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance
    Murata, Yusuke
    Tsuruzoe, Kaku
    Kawashima, Junji
    Furukawa, Noboru
    Kondo, Tatsuya
    Motoshima, Hiroyuki
    Igata, Motoyuki
    Taketa, Kayo
    Sasaki, Kazunari
    Kishikawa, Hideki
    Kahn, C. Ronald
    Toyonaga, Tetsushi
    Araki, Eiichi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 364 (02) : 301 - 307
  • [30] Global IRS-1 phosphorylation analysis in insulin resistance
    Langlais, P.
    Yi, Z.
    Finlayson, J.
    Luo, M.
    Mapes, R.
    De Filippis, E.
    Meyer, C.
    Plummer, E.
    Tongchinsub, P.
    Mattern, M.
    Mandarino, L. J.
    DIABETOLOGIA, 2011, 54 (11) : 2878 - 2889