A stereoselective synthesis of (+)-boronolide

被引:52
|
作者
Ghosh, AK [1 ]
Bilcer, G [1 ]
机构
[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA
关键词
D O I
10.1016/S0040-4039(99)02246-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A stereoselective synthesis of (+)-boronolide is described. The key steps involve a stereoselective reduction of an oc-hydroxy ketone, allylation of an alpha-hydroxy aldehyde and a ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester utilizing Grubbs' catalyst. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1003 / 1006
页数:4
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