Quantitative Simultaneous PET-MR Imaging

被引:2
|
作者
Ouyang, Jinsong [1 ,2 ]
Petibon, Yoann [1 ,3 ]
Huang, Chuan [1 ,2 ]
Reese, Timothy G. [2 ,4 ]
Kolnick, Aleksandra L. [1 ]
El Fakhri, Georges [1 ,2 ]
机构
[1] Massachusetts Gen Hosp, Dept Imaging, Div Nucl Med & Mol Imaging, Ctr Adv Med Imaging Sci, Boston, MA 02114 USA
[2] Harvard Univ, Dept Radiol, Boston, MA 02115 USA
[3] Sorbonne Univ, UPMC Univ Paris 06, CNRS UMR 7371 Lab Imagerie Biomed, Inserm UMRS 1146, F-75013 Paris, France
[4] Martinos Ctr Biomed Imaging, Boston, MA 02129 USA
关键词
PET-MR; motion correction; attenuation correction; point spread function modeling; RESPIRATORY MOTION CORRECTION; ATTENUATION CORRECTION; EMISSION TOMOGRAPHY; PET/MRI EVALUATION; RECONSTRUCTION; LIVER; MODEL; TRANSFORMATION; COMPENSATION; CT;
D O I
10.1117/12.2051578
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Whole-body PET is currently limited by the degradation due to patient motion. Respiratory motion degrades imaging studies of the abdomen. Similarly, both respiratory and cardiac motions significantly hamper the assessment of myocardial ischemia and/or metabolism in perfusion and viability cardiac PET studies. Based on simultaneous PET-MR, we have developed robust and accurate MRI methods allowing the tracking and measurement of both respiratory and cardiac motions during abdominal or cardiac studies. Our list-mode iterative PET reconstruction framework incorporates the measured motion fields into PET emission system matrix as well as the time-dependent PET attenuation map and the position dependent point spread function. Our method significantly enhances the PET image quality as compared to conventional methods.
引用
收藏
页数:9
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