How can we improve the translational landscape for a faster cure of type 1 diabetes?
被引:8
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作者:
von Herrath, Matthias
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机构:
La Jolla Inst Allergy & Immunol, Ctr Type Diabet Res 1, La Jolla, CA 92037 USALa Jolla Inst Allergy & Immunol, Ctr Type Diabet Res 1, La Jolla, CA 92037 USA
von Herrath, Matthias
[1
]
Chan, Andrew
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Genentech Inc, San Francisco, CA 94080 USALa Jolla Inst Allergy & Immunol, Ctr Type Diabet Res 1, La Jolla, CA 92037 USA
Chan, Andrew
[2
]
机构:
[1] La Jolla Inst Allergy & Immunol, Ctr Type Diabet Res 1, La Jolla, CA 92037 USA
Translation of novel therapies for type 1 diabetes and other autoimmune diseases to the clinic has been slow despite significant new initiatives from funding agencies. One reason for this is that different incentives drive industry, academia, and funding bodies. These communities therefore lack common goals and often communicate poorly, resulting in unintended obstacles that hamper progress in efficiently translating basic scientific discoveries into medical practice. Here, based on our own personal experiences, we discuss some of the drivers within each community that cause these problems, existing mechanisms to facilitate the translation of science into medical practice, and remaining issues that need to be solved.
机构:
Univ Paris 05, Necker Enfants Malad Hosp, Pediat Neurol, INSERM U 1129, Paris, France
INSERM U 1129, Fac Med, Strasbourg, FranceUniv Paris 05, Necker Enfants Malad Hosp, Pediat Neurol, INSERM U 1129, Paris, France
机构:
Dept. of Biomaterial Sciences, Grad. Sch. of Agric. and Life Sci., The University of Tokyo, Tokyo, JapanDept. of Biomaterial Sciences, Grad. Sch. of Agric. and Life Sci., The University of Tokyo, Tokyo, Japan