Wall Teichoic Acid in Staphylococcus aureus Host Interaction

被引:69
|
作者
van Dalen, Rob [1 ,2 ]
Peschel, Andreas [1 ,2 ]
van Sorge, Nina M. [3 ,4 ]
机构
[1] Univ Tubingen, Interfac Inst Microbiol & Infect Med, Tubingen, Germany
[2] Univ Tubingen, Cluster Excellence Controlling Microbes Fight Int, Tubingen, Germany
[3] Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Med Microbiol & Infect Prevent, Amsterdam, Netherlands
[4] Netherlands Reference Lab Bacterial Meningitis, Amsterdam, Netherlands
基金
荷兰研究理事会;
关键词
COMPLEMENT-MEDIATED OPSONOPHAGOCYTOSIS; MANNOSE-BINDING PROTEIN; GRAM-POSITIVE BACTERIA; HUMAN LANGERHANS CELLS; LIPOTEICHOIC ACID; TIGHT JUNCTIONS; SKIN; RECEPTOR; INFECTION; PATHWAY;
D O I
10.1016/j.tim.2020.05.017
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Staphylococcus aureus is a major opportunistic human pathogen that frequently causes disease in community and hospital settings. Nasal colonization is an important risk factor for developing invasive disease. Cell wall-associated glycopolymers called wall teichoic acids (WTAs) contribute to efficient nasal colonization by S. aureus. In addition, WTAs are key targets of the host immune system due to their accessibility and high abundance on the S. aureus cell surface. In this review we discuss the new insights into interactions between the host and S. aureus WTA and the implications of these interactions for preventative and therapeutic approaches against S. aureus-mediated disease.
引用
收藏
页码:985 / 998
页数:14
相关论文
共 50 条
  • [31] In Vitro Antimicrobial Activity of Wall Teichoic Acid Biosynthesis Inhibitors against Staphylococcus aureus Isolates
    Suzuki, Takashi
    Swoboda, Jonathan G.
    Campbell, Jennifer
    Walker, Suzanne
    Gilmore, Michael S.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (02) : 767 - 774
  • [32] Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus
    Lee, Kyungae
    Campbell, Jennifer
    Swoboda, Jonathan G.
    Cuny, Gregory D.
    Walker, Suzanne
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (05) : 1767 - 1770
  • [33] Synthesis and Biological Activity of Tetrameric Ribitol Phosphate Fragments of Staphylococcus aureus Wall Teichoic Acid
    Jung, Yoon-Chul
    Lee, Jae-Hyeok
    Kim, Sang Ah
    Schmidt, Timo
    Lee, Wonchul
    Lee, Bok Luel
    Lee, Hee-Seung
    [J]. ORGANIC LETTERS, 2018, 20 (15) : 4449 - 4452
  • [34] An accessory wall teichoic acid glycosyltransferase protects Staphylococcus aureus from the lytic activity of Podoviridae
    Xuehua Li
    David Gerlach
    Xin Du
    Jesper Larsen
    Marc Stegger
    Petra Kühner
    Andreas Peschel
    Guoqing Xia
    Volker Winstel
    [J]. Scientific Reports, 5
  • [35] Wall teichoic acid protects Staphylococcus aureus from inhibition by Congo red and other dyes
    Suzuki, Takashi
    Campbell, Jennifer
    Kim, Younghoon
    Swoboda, Jonathan G.
    Mylonakis, Eleftherios
    Walker, Suzanne
    Gilmore, Michael S.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (09) : 2143 - 2151
  • [36] Wall teichoic acid is an essential component of Staphylococcus aureus for the induction of human dendritic cell maturation
    Hong, Sung Jun
    Kim, Sun Kyung
    Ko, Eun Byeol
    Yun, Cheol-Heui
    Han, Seung Hyun
    [J]. MOLECULAR IMMUNOLOGY, 2017, 81 : 135 - 142
  • [37] An accessory wall teichoic acid glycosyltransferase protects Staphylococcus aureus from the lytic activity of Podoviridae
    Li, Xuehua
    Gerlach, David
    Du, Xin
    Larsen, Jesper
    Stegger, Marc
    Kuehner, Petra
    Peschel, Andreas
    Xia, Guoqing
    Winstel, Volker
    [J]. SCIENTIFIC REPORTS, 2015, 5
  • [38] Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids
    Brown, Stephanie
    Xia, Guoqing
    Luhachack, Lyly G.
    Campbell, Jennifer
    Meredith, Timothy C.
    Chen, Calvin
    Winstel, Volker
    Gekeler, Cordula
    Irazoqui, Javier E.
    Peschel, Andreas
    Walker, Suzanne
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (46) : 18909 - 18914
  • [39] Function and regulation of Staphylococcus aureus wall teichoic acids and capsular polysaccharides
    Keinhoerster, Daniela
    George, Shilpa Elizabeth
    Weidenmaier, Christopher
    Wolz, Christiane
    [J]. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2019, 309 (06)
  • [40] An Antibiotic That Inhibits a Late Step in Wall Teichoic Acid Biosynthesis Induces the Cell Wall Stress Stimulon in Staphylococcus aureus
    Campbell, Jennifer
    Singh, Atul K.
    Swoboda, Jonathan G.
    Gilmore, Michael S.
    Wilkinson, Brian J.
    Walker, Suzanne
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (04) : 1810 - 1820