Stress and oxidative DNA damage in workers with heavy workloads

被引：0

作者：

Irie, M ^{[1
]}

Nagata, S ^{[1
]}

Asami, S ^{[1
]}

Miyata, M ^{[1
]}

Kasai, H ^{[1
]}

机构：

[1] Univ Occupat & Environm Hlth, Inst Ind Ecol Sci, Dept Mental Hlth, Yahatanishi Ku, Kitakyushu, Fukuoka 8078555, Japan

来源：

CONTROL MECHANISMS OF STRESS AND EMOTION: NEUROENDOCRINE-BASED STUDIES | 1999年 / 1185卷

关键词：

catecholamines; cortisol; 8-hydroxydeoxyguanosine; occupational health; perceived workload; working hours;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purpose of this study was to investigate how subjective, or objective physical workload was associated with several kinds of psychobiological parameters including cancer risk in nonsmoking and nondrinking workers. Subjective workload was significantly correlated to the General Health Questionnaire (GHQ) scores (r = 0.39, p < 0.05), and the serum cortisol levels (r = 0.37, p < 0.05), respectively. In turn, long working hours as a measure of objective workload were negatively associated with social support (r = -0.38, p < 0.05), and positively correlated with 8-hydroxydeoxyguanosine (8-OH-dG) levels (r = 0.39, p < 0.05) as a measure of carcinogenicity. Therefore, perceived workload, or long working hours appear to have different impacts on workers' health.

引用

页码：345 / 348

页数：4

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