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Notch around the clock
被引:53
|作者:
Pourquié, O
[1
]
机构:
[1] Univ Mediterranee, AP Marseille, INSERM, CNRS,IBDM,LGPD, F-13288 Marseille 09, France
基金:
澳大利亚研究理事会;
关键词:
D O I:
10.1016/S0959-437X(99)00011-8
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
The establishment of a segmental pattern within the vertebrate body plan is achieved during embryogenesis by the somitogenesis process. Two molecular systems have been implicated in this phenomenon: a molecular clock linked to vertebrate segmentation and the Notch signalling pathway. Rhythmic expression of the Lunatic Fringe gene in the presomitic mesoderm has now provided a link between these two systems.
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页码:559 / 565
页数:7
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