Zebrafish models of myeloid malignancies produced through tet2 and asxl1 genomic editing

被引:0
|
作者
Gjini, Evisa [1 ]
Mansour, Marc [1 ]
Sander, Jeffry [2 ]
He, Shuning [1 ]
Ko, Myunggon [3 ]
Zhou, Yi [4 ]
Rodig, Scott [5 ]
Joung, Keith [6 ]
Zon, Leonard [4 ]
Rao, Anjana [3 ]
Look, Thomas [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
[3] La Jolla Inst Allergy & Immunol, La Jolla, CA USA
[4] Childrens Hosp, Boston, MA 02115 USA
[5] Brigham & Womens Hosp, Boston, MA 02115 USA
[6] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
D O I
10.1158/1538-7445.AM2015-5152
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5152
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice
    Zhao, Zhigang
    Chen, Li
    Dawlaty, Meelad M.
    Pan, Feng
    Weeks, Ophelia
    Zhou, Yuan
    Cao, Zeng
    Shi, Hui
    Wang, Jiapeng
    Lin, Li
    Chen, Shi
    Yuan, Weiping
    Qin, Zhaohui
    Ni, Hongyu
    Nimer, Stephen D.
    Yang, Feng-Chun
    Jaenisch, Rudolf
    Jin, Peng
    Xu, Mingjiang
    CELL REPORTS, 2015, 13 (08): : 1692 - 1704
  • [42] DNMT3A, TET2, and ASXL1 (DTA) Mutations Are Associated with Thrombosis and Bleeding in Patients with Myeloproliferative Neoplasms
    Haran, Arnon
    Wasserstrom, Avital
    Aumann, Shlomzion
    Vainstein, Vladimir
    Kazoom, Romi
    Jelinek, Batia Roth
    Arad, Ariela
    Buchman, Noa
    Shai, Ela
    Kalish, Yossi
    Gatt, Moshe E.
    Zimran, Eran
    BLOOD, 2024, 144 : 3189 - 3190
  • [43] Coordinate regulation of chromatin state by JAK2 and ASXL1 mutations in myeloid malignancies
    LaFave, Lindsay M.
    Chung, Young Rock
    Keller, Matt
    Kleppe, Maria
    Mullally, Ann
    Abdel-Wahab, Omar
    Levine, Ross L.
    CANCER RESEARCH, 2013, 73
  • [44] Molecular Screening In Blastic Plasmacytoid Dendritic Cell Neoplasms Reveals Mutations In TET2 and ASXL1 In The Majority Of Patients
    Kern, Wolfgang
    Kuznia, Sabrina
    Schnittger, Susanne
    Haferlach, Claudia
    Haferlach, Torsten
    Kohlmann, Alexander
    BLOOD, 2013, 122 (21)
  • [45] New TET2, ASXL1 and CBL Mutations Have Poor Prognostic Impact In Systemic Mastocytosis and Related Disorders
    Traina, Fabiola
    Jankowska, Ania
    Makishima, Hideki
    Hsieh, Fred H.
    Han, Yingchun
    O'Keefe, Christine
    Sugimoto, Yuka
    Mohan, Sanjay R.
    Szpurka, Hadrian
    Prince, Courtney
    Guinta, Kathryn
    Sekeres, Mikkael A.
    Kalaycio, Matt
    Lichtin, Alan E.
    Advani, Anjali S.
    Copelan, Edward
    Sobecks, Ronald
    Maciejewski, Jaroslaw P.
    Tiu, Ramon V.
    BLOOD, 2010, 116 (21) : 1268 - 1269
  • [46] Mutations in ASXL1 and/or TET2 Identify a Subset with Worse Outcomes in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasms
    Xu, Mina
    Thakkar, Devang
    Panse, Gauri
    Yan, Jiong
    Minden, Mark
    Zandi, Sasan
    Naresh, Kikkeri
    Czader, Magdalena
    Love, Cassandra
    Happ, Lanie
    Koff, Jean
    Jaye, David
    Michael, Churnetski
    Arildsen, Mary Ann
    Juskevicius, Ridas
    Soliman, Dina
    Louissaint, Abner
    Mckinney, Matthew
    Sojitra, Payal
    Yin, C. Cameron
    Ondrejka, Sarah
    Tse, Eric
    Dave, Sandeep
    LABORATORY INVESTIGATION, 2023, 103 (03) : S1258 - S1259
  • [47] Gain-of-Function of ASXL1 Truncating Protein in the Pathogenesis of Myeloid Malignancies
    Yang, Hui
    Kurtenbach, Stefan
    Guo, Ying
    Lohse, Ines
    Durante, Michael
    Zhang, Peng
    Zhou, Yuan
    Harbour, William
    Wahlestedt, Claes
    Xu, Mingjiang
    Yang, Feng-Chun
    BLOOD, 2017, 130
  • [48] Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia
    Cui Y.
    Tong H.
    Du X.
    Li B.
    Gale R.
    Qin T.
    Liu J.
    Xu Z.
    Zhang Y.
    Huang G.
    Jin J.
    Fang L.
    Zhang H.
    Pan L.
    Hu N.
    Qu S.
    Xiao Z.
    Experimental Hematology & Oncology, 4 (1)
  • [49] Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutations
    Ohgami, Robert S.
    Ma, Lisa
    Merker, Jason D.
    Gotlib, Jason R.
    Schrijver, Iris
    Zehnder, James L.
    Arber, Daniel A.
    MODERN PATHOLOGY, 2015, 28 (05) : 706 - 714
  • [50] RAS Mutations in Adult Acute Myeloid Leukemia (AML). Frequency, Mutational Spectrum, and Identification of a Comutation Bias for KRASK117 (TET2/ASXL1)
    Artigas-Baleri, Alicia
    Castellet, Helena
    Pratcorona, Marta
    Zamora, Lurdes
    Lopez-Guerra, Monica
    Tazon, Barbara
    Vives, Susana
    Tormo, Mar
    Arnan, Montserrat
    Garcia-Guinon, Antoni
    Coll, Rosa
    Sampol, Antonia
    Bargay, Joan
    Vall-Llovera, Ferran
    Salamero, Olga
    Lopez-Cadenas, Felix
    Garrido Diaz, Ana
    Esteve, Jordi
    Sierra, Jorge
    Nomdedeu, Josep F.
    BLOOD, 2022, 140 : 11821 - 11823