3D genomics imposes evolution of the domain model of eukaryotic genome organization (vol 126, pg 59, 2017)

被引：0

作者：

Razin, Sergey V. ^{[1
,2
,3
]}

Vassetzky, Yegor S. ^{[2
,3
,4
]}

机构：

[1] RAS, Inst Gene Biol, Moscow, Russia

[2] LIA1066 French Russian Canc Res Lab, Villejuif, France

[3] Lomonosov Moscow State Univ, Moscow, Russia

[4] Univ Paris Sud Paris Saclay, Inst Gustave Roussy, CNRSUMR8126, 39 Rue Camille Desmoulins, F-94805 Villejuif, France

来源：

CHROMOSOMA | 2017年 / 126卷 / 01期

基金：

俄罗斯科学基金会;

关键词：

Chromatin; Domains; Epigenetics; Large-scale organization;

D O I：

10.1007/s00412-016-0623-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The hypothesis that the genome is composed of a patchwork of structural and functional domains (units) that may be either active or repressed was proposed almost 30 years ago. Here, we examine the evolution of the domain model of eukaryotic genome organization in view of the expansion of genome-scale techniques in the twenty-first century that have provided us with a wealth of information on genome organization, folding, and functioning.

引用

页码：71 / 71

页数：1

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