Transcription regulation mechanisms of bacteriophages Recent advances and future prospects

被引:40
|
作者
Yang, Haiquan [1 ]
Ma, Yingfang [1 ]
Wang, Yitian [1 ]
Yang, Haixia [2 ]
Shen, Wei [1 ]
Chen, Xianzhong [1 ]
机构
[1] Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Ind Biotechnol, Wuxi, Peoples R China
[2] Shandong Acad Pharmaceut Sci, Jinan, Peoples R China
关键词
bacteriophages; transcription; regulation mechanism; RNA polymerase; promoter; COLI RNA-POLYMERASE; TEMPORAL REGULATION; STRUCTURAL BASIS; GENE-EXPRESSION; ACTIVATOR MOTA; BETA-SUBUNIT; SIGMA-FACTOR; PHAGE; COACTIVATOR; ARCHITECTURE;
D O I
10.4161/bioe.32110
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Phage diversity significantly contributes to ecology and evolution of new bacterial species through horizontal gene transfer. Therefore, it is essential to understand the mechanisms underlying phage-host interactions. After initial infection, the phage utilizes the transcriptional machinery of the host to direct the expression of its own genes. This review presents a view on the transcriptional regulation mechanisms of bacteriophages, and its contribution to phage diversity and classification. Through this review, we aim to broaden the understanding of phage-host interactions while providing a reference source for researchers studying the regulation of phage transcription.
引用
收藏
页码:300 / 304
页数:5
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