New ingredients for brewing CD4+ T (cells): TCF-1 and LEF-1

被引：3
|
作者：
Mookerjee-Basu, Jayati [1 ]
Kappes, Dietmar J. [1 ]
机构：
[1] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA
来源：
NATURE IMMUNOLOGY | 2014年 / 15卷 / 07期
关键词：
THYMOCYTE DIFFERENTIATION; TRANSCRIPTION FACTORS; LINEAGE COMMITMENT; POSITIVE SELECTION; REPRESSION; POK;
D O I：
10.1038/ni.2927
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The transcription factors TCF-1 and LEF-1 have diverse roles in differentiation into the CD4(+) lineage through means both dependent on and independent of the transcription factor Th-POK.
引用
收藏
页码：593 / 594
页数：2
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