Development of dog mammary tumor xenograft in immunosuppressed Swiss albino mice

被引：0

作者：

Rajmani, R. S. ^{[1
]}

Singh, Prafull Kumar ^{[1
]}

Kumar, Sanjay ^{[2
]}

Kumar, G. Ravi ^{[1
]}

Sahoo, Aditya P. ^{[1
]}

Santra, Lakshman ^{[1
]}

Saxena, Shikha ^{[1
]}

Singh, Lakshya Veer ^{[1
]}

Chaturvedi, Uttara ^{[1
]}

Saxena, Lovleen ^{[1
]}

Desai, G. S. ^{[1
]}

Gupta, Shishir Kumar ^{[1
]}

Kumar, Amit ^{[3
]}

Jadon, N. S. ^{[2
]}

Tiwari, Ashok K. ^{[1
]}

机构：

[1] Indian Vet Res Inst, Div Vet Biotechnol, Mol Biol Lab, Bareilly 243122, Uttar Pradesh, India

[2] Govind Ballabh Pant Univ Agr & Technol, Div Surg, Pantnagar 263145, Uttar Pradesh, India

[3] Indian Vet Res Inst, Div Anim Genet & Breeding, Bareilly 243122, Uttar Pradesh, India

来源：

INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY | 2014年 / 52卷 / 10期

关键词：

Dog mammary tumour; Immunosuppression; Xenograft; T-CELLS; BREAST-CANCER; CYCLOSPORIN-A; IFN-GAMMA; IMMUNITY; RESPONSES; MODELS; IMMUNOLOGY; MELANOMA; IMMUNOTHERAPY;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Development and study of dog mammary tumour xenograft in immunosuppressed Swiss Albino Mice adds a new dimension in cancer research as dog tumors have many similarities with human tumors regarding progression, histopathology, molecular mechanism, immune response and therapy. Failure of the immune system to recognize and eliminate cancer cells leads to cancer progression and the fight between immune cells and cancer cells has a great role in understanding the mechanism of cancer progression and elimination. Rejection and acceptance of tumour xenograft depends on efficiency of CD4(+), CD8(+) and NK cell populations. In the present investigation, dog mammary tumor xenograft in cyclosporine-A and gamma-irradiated, immunosuppressed Swiss Albino mice was developed and the immune cell status of graft accepted and rejected mice was assessed. It was observed that all the major immune cells (CD4+, CD8+ and NK cells) play an equal role in tumour rejection.

引用

页码：935 / 942

页数：8

共 50 条

[31] SEGREGATION MAMMARY CANCER TO NO MAMMARY CANCER IN THE MARSH ALBINO STRAIN OF MICE
MURRAY, WS
WARNER, SG
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1947, 7 (04) : 183 - 188
[32] ENHANCEMENT OF CARCINOGENESIS BY PROSTAGLANDINS IN MALE ALBINO SWISS MICE
LUPULESCU, A
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1978, 61 (01) : 97 - 106
[33] Radioprotection of Swiss albino mice by Myristica fragrans houtt
Sharma, Mini
Kumar, Madhu
JOURNAL OF RADIATION RESEARCH, 2007, 48 (02) : 135 - 141
[34] COMPARABLE TECHNIQUE FOR CHEMICAL THYROIDECTOMY IN SWISS ALBINO MICE
BHAI, I
PANDEY, AK
NATIONAL ACADEMY SCIENCE LETTERS-INDIA, 1978, 1 (09): : 347 - &
[35] MARKED VARIATION IN DIAZEPAM SENSITIVITY IN SWISS ALBINO MICE
WONG, PTH
YOONG, YL
GWEE, MCE
LIFE SCIENCES, 1986, 39 (11) : 945 - 952
[36] EFFECT OF CARBON-MONOXIDE ON SWISS ALBINO MICE
HILADO, CJ
CUMMING, HJ
JOURNAL OF COMBUSTION TOXICOLOGY, 1977, 4 (02): : 216 - 230
[37] Evaluation of Analgesic Activity of Benzapril in Swiss Albino Mice
Amoghimath, Siddamma
Suresha, R. N.
Vaibhavi, P. S.
Shruthi, S. L.
Shashidhar, G.
INDIAN JOURNAL OF PHARMACOLOGY, 2013, 45 : S115 - S115
[38] CARCINOGENIC EFFECT OF GIBBERELLIN A(3) IN SWISS ALBINO MICE
ELMOFTY, MM
SAKR, SA
RIZK, AM
MOUSSA, EA
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1994, 21 (02): : 183 - 190
[39] Antigenotoxic Potential of Garcinia Indicain Swiss Albino Mice
Khatib, N. A.
Singh, Kumar Ajay Umashankar
Pundir, Charu
INDIAN JOURNAL OF PHARMACOLOGY, 2013, 45 : S214 - S214
[40] Immunomodulatory Efficiency of Abelmoschus esculentus in Swiss Albino Mice
Narayanan, K. R.
Dhasarathan, P.
Manujula, M.
Thenmozhi, M.
INDIAN JOURNAL OF ANIMAL RESEARCH, 2021, 55 (04) : 401 - 406

← 1 2 3 4 5 →