Genetic analysis for JNK-mediated apoptosis

被引：2
|
作者：
Kuranaga, E [1 ]
Miura, M [1 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Dept Genet, Bunkyo Ku, Tokyo 1130033, Japan
来源：
ACTA HISTOCHEMICA ET CYTOCHEMICA | 2004年 / 37卷 / 04期
关键词：
JNK; IAPs; ASK1; TRAFs; apoptosis;
D O I：
10.1267/ahc.37.223
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Recent genetic studies revealed crucial roles of JNK (c-jun N-terminal kinase) activation in cell death. However, the molecular mechanisms underlying JNK-mediated cell death are largely unknown. We present one of the JNK-mediated apoptotic mechanism is regulated by a ubiquitine-proteasome system.
引用
收藏
页码：223 / 226
页数：4
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