Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones by domino reactions of amino acids with ynones

被引：3
|
作者：
Miliutina, Mariia [1 ]
Ivon, Yevhen [1 ,2 ]
Slobodyanyuk, Evgeniy Y. [1 ,2 ]
Ejaz, Syeda Abida [3 ]
Iqbal, Jamshed [3 ]
Villinger, Alexander [1 ]
Iaroshenko, Viktor O. [1 ,4 ]
Langer, Peter [1 ,5 ]
机构：
[1] Univ Rostock, Inst Chem, 3a Albert Einstein St, D-18059 Rostock, Germany
[2] Taras Shevchenko Natl Univ Kyiv, 62 Volodymyrska St, UA-01033 Kiev, Ukraine
[3] COMSATS Inst Informat Technol, Ctr Adv Drug Res, Abbottabad 22060, Pakistan
[4] Ctr Mol & Macromol Studies, 112 Sienkiewicza St, PL-90363 Lodz, Poland
[5] Univ Rostock, Leibniz Inst Katalyse eV, 29a Albert Einstein St, D-18059 Rostock, Germany
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2019年 / 55卷 / 4-5期
关键词：
amino acids; chromeno[2; 3-c]pyrrol-9(2H)-ones; heterocycles; alkaline phosphatase inhibitory activity; domino reactions; DISCOVERY;
D O I：
10.1007/s10593-019-02481-x
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic ,-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.
引用
收藏
页码：465 / 468
页数：4
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