Advances and challenges in the prevention and treatment of COVID-19

被引：14

作者：

Han, Yan-Jie ^{[1
,2
,3
]}

Ren, Zhi-Guang ^{[1
,2
]}

Li, Xin-Xin ^{[3
]}

Yan, Ji-Liang ^{[3
]}

Ma, Chun-Yan ^{[3
]}

Wu, Dong-Dong ^{[1
,2
,4
]}

Ji, Xin-Ying ^{[1
,2
]}

机构：

[1] Henan Univ, Sch Basic Med Sci, Kaifeng Key Lab Infect Dis & Biosafety, Kaifeng 475004, Henan, Peoples R China

[2] Henan Univ, Sch Basic Med Sci, Henan Int Joint Lab Nucl Prot Regulat, Kaifeng 475004, Henan, Peoples R China

[3] Kaifeng Cent Hosp, Clin Lab & Funct Lab, Kaifeng 475000, Henan, Peoples R China

[4] Henan Univ, Sch Stomatol, Kaifeng 475004, Henan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2020年 / 17卷 / 12期

基金：

中国国家自然科学基金;

关键词：

SARS-CoV-2; COVID-19; virological characteristics; clinical treatment; drugs; RESPIRATORY SYNDROME CORONAVIRUS; VITRO ANTIVIRAL ACTIVITY; FAVIPIRAVIR T-705; SARS-COV; MERS-COV; RIBAVIRIN; VIRUS; REPLICATION; ACE2; INHIBITORS;

D O I：

10.7150/ijms.47836

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Since the end of 2019, a new type of coronavirus pneumonia (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been spreading rapidly throughout the world. Previously, there were two outbreaks of severe coronavirus caused by different coronaviruses worldwide, namely Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). This article introduced the origin, virological characteristics and epidemiological overview of SARS-CoV-2, reviewed the currently known drugs that may prevent and treat coronavirus, explained the characteristics of the new coronavirus and provided novel information for the prevention and treatment of COVID-19.

引用

页码：1803 / 1810

页数：8

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