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Cent S Univ, Xiangya Hosp, Key Cite Natl Clin Res Ctr Resp Dis, Dept Resp Med, Changsha, Hunan, Peoples R China Cent S Univ, Xiangya Hosp, Key Cite Natl Clin Res Ctr Resp Dis, Dept Resp Med, Changsha, Hunan, Peoples R China