Droloxifene does not blunt the bone anabolic effects of prostaglandin E(2) (PGE(2)) but maintains the PGE(2)-restored bone in osteopenic rats.

被引：0
|
作者：
Thompson, DD [1 ]
Oi, H [1 ]
Crawford, DT [1 ]
Pirie, CM [1 ]
Simmons, HA [1 ]
Ke, HZ [1 ]
机构：
[1] PFIZER INC,DIV CENT RES,GROTON,CT 06340
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 1996年 / 11卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1 / 1
页数：1
相关论文
共 50 条
  • [21] PROSTAGLANDIN-E2 (PGE2) LEVELS IN ALVEOLAR BONE OF ORTHODONTICALLY-TREATED CATS
    DAVIDOVITCH, Z
    SHANFELD, JL
    JOURNAL OF DENTAL RESEARCH, 1980, 59 : 977 - 977
  • [22] Recovery of rhBMP-2 bone inductive activity by PTH, VitD and PGE2 in aged rats.
    Kabasawa, Y
    Asahina, I
    Gunji, A
    Enomoto, S
    JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S338 - S338
  • [23] Discovery of highly selective EP4 receptor prostaglandin E2 (PGE2) Agonists which stimulate new bone formation and restore bone mass in ovariectomized rats.
    Cameron, KO
    Lefker, BA
    Crawford, DT
    DaSilvaJardine, P
    DeNinno, SL
    Grasser, WA
    Ke, HZ
    Lu, B
    Owen, TA
    Paralkar, VM
    Si, H
    Scott, DO
    Thompson, DD
    Tjoa, CM
    Zawistoski, MP
    JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S484 - S484
  • [24] Discovery of a non-prostanoid EP2 receptor selective prostaglandin E2 (PGE2) agonist that mimics the local anabolic effects of PGE2.
    Ke, HZ
    Qi, H
    Crawford, DT
    Chidsey-Frink, KL
    Cameron, KO
    Lefker, BA
    Paralkar, VM
    Owen, TA
    Li, M
    Lu, B
    Grasser, WA
    Yu, L
    DaSilva-Jardine, P
    Thompson, DD
    JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S377 - S377
  • [25] A non-prostanoid EP4 receptor selective prostaglandin E2 (PGE2) agonist stimulates bone formation and restores bone mass and strength in ovariectomized rats.
    Ke, HZ
    Crawford, DT
    Ol, H
    Li, M
    Paralkar, VM
    Owen, TA
    Pan, LC
    Brown, TA
    Cameron, KO
    Lefker, BA
    DaSilva-Jardine, P
    Lu, B
    Grasser, WA
    Simmons, HA
    Yu, LJ
    Scott, DO
    Thompson, DD
    JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S483 - S483
  • [26] Systemic administration of an anabolic dose of PGE(2) in young rats increases the osteogenic capacity of bone marrow
    Weinreb, M
    Suponitzky, I
    Keila, S
    BONE, 1997, 20 (06) : 521 - 526
  • [27] Prostaglandin receptor EP4 mediates the bone anabolic effects of PGE2 (vol 60, pg 36, 2001)
    Machwate, M
    Harada, S
    Leu, CT
    Seedor, G
    Labelle, M
    Gallant, M
    Hutchins, S
    Lachance, N
    Sawyer, N
    Slipetz, D
    Metters, KM
    Rodan, SB
    Young, R
    Rodan, GA
    MOLECULAR PHARMACOLOGY, 2003, 64 (01) : 192 - 192
  • [28] Anabolic effect of prostaglandin E2 in bone is not dependent on pituitary hormones in rats
    Chen, MM
    Yeh, JK
    Aloia, JF
    CALCIFIED TISSUE INTERNATIONAL, 1998, 63 (03) : 236 - 242
  • [29] Anabolic Effect of Prostaglandin E2 in Bone Is not Dependent on Pituitary Hormones in Rats
    M. M. Chen
    J. K. Yeh
    J. F. Aloia
    Calcified Tissue International, 1998, 63 : 236 - 242
  • [30] PROSTAGLANDIN PGE2 - POSSIBLE MECHANISM FOR BONE DESTRUCTION IN CALCINOSIS CIRCUMSCRIPTA
    CANIGGIA, A
    GENNARI, C
    VATTIMO, A
    RUNCI, F
    BOMBARDIERI, S
    CALCIFIED TISSUE RESEARCH, 1978, 25 (01): : 53 - 57
12345