The prevalence and outcome of short-acting β2-agonists overuse in asthma patients in Taiwan

被引：14
|
作者：
Wang, Cheng-Yi [1 ,2 ]
Lai, Chih-Cheng [3 ]
Wang, Ya-Hui [2 ,4 ]
Wang, Hao-Chien [5 ,6 ]
机构：
[1] Fu Jen Catholic Univ, Dept Internal Med, Cardinal Tien Hosp, New Taipei, Taiwan
[2] Fu Jen Catholic Univ, Coll Med, Sch Med, New Taipei, Taiwan
[3] Kaohsiung Vet Gen Hosp, Tainan Branch, Dept Internal Med, Tainan, Taiwan
[4] Fu Jen Catholic Univ, Med Res Ctr, Cardinal Tien Hosp, New Taipei, Taiwan
[5] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan
[6] Natl Taiwan Univ, Coll Med, Taipei, Taiwan
来源：
NPJ PRIMARY CARE RESPIRATORY MEDICINE | 2021年 / 31卷 / 01期
关键词：
INHALED CORTICOSTEROIDS; PREVENTION;
D O I：
10.1038/s41533-021-00231-1
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This study aims to investigate the prevalence of short-acting beta 2-agonist (SABA) overuse in asthma and the associated risk of acute exacerbation and mortality in Taiwan. We used the Taiwanese pay-for-performance asthma program database, which included patients aged between 12 and 100 years who were enrolled in the program between 2001 and 2015. Among a total of 218,039 patients, 34,641 (15.9%) patients are classified as SABA over-users. Compared with patients who did not receive inhaled corticosteroids (ICS) and collected <= 2 canisters, SABA over-users had a higher risk of severe exacerbations. SABA over-users had a higher risk of all-cause mortality compared with patients who did not receive ICS and collected <= 2 canisters. The overall prevalence of SABA overuse in Taiwan is 15.9%, and this is even higher in concomitant ICS users. In addition, the overuse of SABA is associated with an increased risk of severe exacerbation and death.
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页数：7
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